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US4304910A Expired / Lapsed US ⏱️ 0.0 years remaining

Quarnary ammonium polymeric anti-microbial agent

Assignee: Stepan Co
•
Filing: 1979-04-13
•
Granted: 1981-12-08
•
Expires: 1999-04-13
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Abstract

Abstract A method for synthesizing compounds of formula: ##STR1## in which R' and R" (I) are the same or different monovalent branched or unbranched alkyl groups of from 1 to 18 carbon atoms, optionally substituted by from 1 to 2 hydroxyl groups, the sum of the carbon atoms in R' and R" being at least three; or (II) form a 5, 6, or seven membered ring when taken together with N; or (III) form the N-Morpholino group when taken together with N and Oxygen, wherein Z represents either X or --N R'R", wherein X is a halogen of atomic weight above 30, and wherein n represents an integer of from 2 to 20.

Inventors

  • 👤 Harold A. Green
  • 👤 John J. Merianos
  • 👤 Alfonso N. Petrocci

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 21:59
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/84; A01; A01N; A01N33/00; A01N33/02; A01N33/12; A61K8/30; A61K8/40; A61K8/41; A61K8/416; C; C08; C08G; C08G73/00; C08G73/02; C08G73/0206; C08G73/0213; C08G73/0226; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5426; A61Q; A61Q5/00; A61Q5/12

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 126 words
A compound or mixture of compounds formed by the reaction between R'R"NCH 2 CHOHCH 2 NR'R" and an approximately equimolar quantity of 1,3-dihalo-2-propanol at a temperature of between about 40° C. and about 95° C. for between about 2 to about 12 hours, R' and R" being either (I) the same or different monovalent, branched or unbranched alkyl groups of from 1 to 18 carbon atoms either unsubstituted or substituted by either 1 or 2 hydroxyl groups, the sum of the carbon atoms in R' and R" being at least 3, or (II) form a 5, 6 or 7 membered monoheterocyclic saturated ring when taken together with N, the hetero atom being nitrogen or (III) when taken together with nitrogen and oxygen form the N-morpholino group.
Claim 2
Dependent Claim 126 words
A compound or mixture of compounds formed by the reaction between R'R"NCH 2 CHOHCH 2 NR'R" and an approximately equimolar quantity of 1,3-dihalo-2-propanol at a temperature of between about 40° C. and about 95° C. for between about 2 to about 12 hours, R' and R" being either (I) the same or different monovalent, branched or unbranched alkyl groups of from 1 to 18 carbon atoms either unsubstituted or substituted by either 1 or 2 hydroxyl groups, the sum of the carbon atoms in R' and R" being at least 3, or (II) form a 5, 6 or 7 membered monoheterocyclic saturated ring when taken together with N, the hetero atom being nitrogen or (III) when taken together with nitrogen and oxygen form the N-morpholino group.
Claim 3
Dependent Claim 27 words
The product of claim 1 in which at least 50% by weight of the mixture of products are compounds in which n is between 2 and 5.
Claim 4
Dependent Claim 8 words
The product of claim 1 in which ##STR5##
Claim 5
Dependent Claim 12 words
The product of claim 1 in which R'═R"═C 2 H 5 .
Claim 6
Dependent Claim 12 words
The product of claim 1 in which R'═R"═-CH(CH 3 ) 2 .
Claim 7
Dependent Claim 12 words
The product of claim 1 in which R'--R"═--CH 2 CH 2 OH.
Claim 8
Dependent Claim 12 words
The product of claim 1 in which R'═R"═--C 4 H 9 .
Claim 9
Dependent Claim 12 words
The product of claim 1 in which R'═R"═--C 8 H 17 .
Claim 10
Dependent Claim 15 words
The product of claim 1 in which R'═--CH 3 and R"═--C 12 H 25 .
Claim 11
Dependent Claim 8 words
The product of claim 1 in which ##STR6##

References Cited (Backward Citations)

US2941004A Cited
US2933529A Cited
US3725312A Cited
US3738495A Cited
US4027009A Cited
US4196217A Cited
US4089977A Cited
US4111679A Cited
US4250112A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-12-07 1985-06-08 1985-12-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-12-07 1989-06-08 1989-12-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-12-07 1993-06-08 1993-12-08 $7700.00 Window Closed / Lapsed

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