US4301140A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Radiopharmaceutical method for monitoring kidneys
Assignee: GD Searle LLC
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Filing: 1979-12-14
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Granted: 1981-11-17
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Expires: 1999-12-14
Abstract
Abstract Complexes of technetium-99m with fructose 6-phosphate or fructose 1,6-diphosphate or salts thereof having utility as radiopharmaceutical agents for monitoring the activity of an organ, their preparation and a method employing such complexes for externally monitoring the activity of an organ are disclosed.
Inventors
- 👤 Patricia Frank
- 👤 Stephen Kraychy
- 👤 Ernest F. Le Von
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 22:29
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/0491; A61K2123/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
60 words
A method of externally monitoring the kidneys comprising administering intravenously to a patient a solution of a complex of technetium-99m and a compound having the formula ##STR2## or a pharmaceutically acceptable salt thereof, wherein R is --H or --PO 3 H 2 , and monitoring radiographically the distribution of the complex in the patient and its clearance through the kidneys.
Claim 2
Independent Claim
60 words
A method of externally monitoring the kidneys comprising administering intravenously to a patient a solution of a complex of technetium-99m and a compound having the formula ##STR2## or a pharmaceutically acceptable salt thereof, wherein R is --H or --PO 3 H 2 , and monitoring radiographically the distribution of the complex in the patient and its clearance through the kidneys.
Claim 3
Dependent Claim
9 words
The method of claim 1 wherein R is --H.
Claim 4
Dependent Claim
13 words
The method of claim 1 wherein R is --PO 3 H 2 .
Claim 5
Dependent Claim
14 words
The method of claim 1 wherein a sodium salt of the complex is employed.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-16 | 1985-05-18 | 1985-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-16 | 1989-05-18 | 1989-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-16 | 1993-05-18 | 1993-11-17 | $7700.00 | Window Closed / Lapsed |