US4299501A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Continuous process for the preparation of semisolid dispersions
Assignee: Ortho Pharmaceutical Corp
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Filing: 1979-08-10
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Granted: 1981-11-10
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Expires: 1999-08-10
Abstract
Abstract A semicontinuous or continuous process for preparing semisolid dispersions is provided wherein oil and water phases are circulated from a single vessel through a system of mixers and homogenizers until a dispersion is obtained.
Inventors
- 👤 Deepak R. Patil
- 👤 Glenn A. VanBuskirk
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 15:29
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/107; B; B01; B01F; B01F23/00; B01F23/40; B01F23/49; B01F35/00; B01F35/90
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
54 words
A process for preparing a semisolid dispersion which comprises circulating a mixture of an oil phase and an aqueous phase from a main vessel through one or more mixing devices and one or more homogenizers in series until a semisolid dispersion is formed and withdrawing the dispersion from the system through a heat exchanger.
Claim 2
Dependent Claim
54 words
A process for preparing a semisolid dispersion which comprises circulating a mixture of an oil phase and an aqueous phase from a main vessel through one or more mixing devices and one or more homogenizers in series until a semisolid dispersion is formed and withdrawing the dispersion from the system through a heat exchanger.
Claim 3
Dependent Claim
67 words
The process of claim 1 wherein the aqueous phase is first circulated through the mixers and homogenizers at an elevated temperature, followed by addition of the oil phase to the aqueous phase, after which the mixture of the two phases is circulated through the mixers and homogenizers at elevated temperatures until a dispersion is formed after which the dispersion is withdrawn from circulation through a heat exchanger.
Claim 4
Dependent Claim
26 words
The process of claim 2 wherein the temperature of the water phase and the oil and water phase is about 5° F. above the congealing point.
Claim 5
Dependent Claim
78 words
A process for the continuous preparation of a semisolid dispersion which comprises circulating a mixture of an oil phase and aqueous phase from a main vessel through one or more mixing devices and one or more homogenizers in series until a semisolid dispersion is formed, withdrawing a portion of said dispersion from the system at intervals through a heat exchanger while adding an amount of the mixture of the oil and aqueous phases equal to the amount withdrawn.
Claim 6
Dependent Claim
78 words
A process for the continuous preparation of a semisolid dispersion which comprises circulating a mixture of an oil phase and aqueous phase from a main vessel through one or more mixing devices and one or more homogenizers in series until a semisolid dispersion is formed, withdrawing a portion of said dispersion from the system at intervals through a heat exchanger while adding an amount of the mixture of the oil and aqueous phases equal to the amount withdrawn.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-09 | 1985-05-11 | 1985-11-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-09 | 1989-05-11 | 1989-11-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-09 | 1993-05-11 | 1993-11-10 | $7700.00 | Window Closed / Lapsed |