US4296244A
Expired / Lapsed
US
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(3-Trifluoromethylphenyl)-alpha-hydroxyacetic acid and process for preparation
Assignee: Occidental Chemical Corp
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Filing: 1979-11-07
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Granted: 1981-10-20
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Expires: 1999-11-07
Abstract
Abstract The present invention provides a novel organic compound, (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid, and a process for the preparation thereof comprising the steps of: a. converting (3-trifluoromethyl)-benzotrichloride to the corresponding benzoyl chloride, b. cyanation of the benzoyl chloride to produce the corresponding benzoyl cyanide, c. hydrolyzing the benzoyl cyanide to produce the corresponding keto-acid, and d. hydrogenating the keto-acid to produce (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid.
Inventors
- 👤 David Y. Tang
- 👤 Arthur M. Foster
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 11:24
CPC Classifications
C; C07; C07C; C07C255/00; C07C51/00; C07C51/58; C07C59/00; C07C59/40; C07C59/42; C07C59/56; C07C59/76; C07C59/88
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
2 words
(3-trifluoromethylphenyl)-alpha-hydroxyacetic acid.
Claim 2
Dependent Claim
2 words
(3-trifluoromethylphenyl)-alpha-hydroxyacetic acid.
Claim 3
Dependent Claim
62 words
A process of producing (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid comprising the steps of: (a) reacting (3-trifluoromethyl)-benzotrichloride with water to form the corresponding benzoyl chloride, (b) cyanation of the benzoyl chloride by reaction with CuCN to produce the corresponding benzoyl cyanide, (c) hydrolyzing the benzoyl cyanide to produce the corresponding keto-acid, (d) hydrogenating the keto-acid in the presence of an hydrogenation catalyst to produce (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid.
Claim 4
Dependent Claim
62 words
A process of producing (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid comprising the steps of: (a) reacting (3-trifluoromethyl)-benzotrichloride with water to form the corresponding benzoyl chloride, (b) cyanation of the benzoyl chloride by reaction with CuCN to produce the corresponding benzoyl cyanide, (c) hydrolyzing the benzoyl cyanide to produce the corresponding keto-acid, (d) hydrogenating the keto-acid in the presence of an hydrogenation catalyst to produce (3-trifluoromethylphenyl)-alpha-hydroxyacetic acid.
Claim 5
Dependent Claim
20 words
The process of claim 2 wherein step (a) is carried out at temperatures between about 120° and about 130° C.
Claim 6
Dependent Claim
16 words
The process of claim 2 wherein step (a) is catalyzed and the catalyst is ferric chloride.
Claim 7
Dependent Claim
20 words
The process of claim 2 wherein step (b) is carried out at temperatures between about 170° and about 200° C.
Claim 8
Dependent Claim
18 words
The process of claim 2 wherein step (c) is carried out in the presence of concentrated hydrochloric acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-10-19 | 1985-04-20 | 1985-10-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-10-19 | 1989-04-20 | 1989-10-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-10-19 | 1993-04-20 | 1993-10-20 | $7700.00 | Window Closed / Lapsed |