US4294819A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Alkaline analgesic capsule
Assignee: Bristol Myers Co
•
Filing: 1980-08-18
•
Granted: 1981-10-13
•
Expires: 2000-08-18
Abstract
Abstract There is disclosed a capsule containing aspirin and alternatively other active analgesic materials in combination with an alkaline material. The composition is made stable by providing the alkaline material in a tablet form.
Inventors
- 👤 Thomas M. Tencza
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 20:13
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4808
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
90 words
As a unit dosage form a capsule having incorporated therein an alkaline tablet having a fast distintegration rate and an aspirin mixture; said aspirin mixture being present in said capsule as a powder or granulated material; said aspirin being present in said capsule at a level in the range of from about 160 mg. to about 500 mg. per capsule; and the quantity of alkaline material contained in said capsule being between about 30% to about 100% by weight based on the total weight of aspirin contained in the capsule.
Claim 2
Dependent Claim
90 words
As a unit dosage form a capsule having incorporated therein an alkaline tablet having a fast distintegration rate and an aspirin mixture; said aspirin mixture being present in said capsule as a powder or granulated material; said aspirin being present in said capsule at a level in the range of from about 160 mg. to about 500 mg. per capsule; and the quantity of alkaline material contained in said capsule being between about 30% to about 100% by weight based on the total weight of aspirin contained in the capsule.
Claim 3
Dependent Claim
25 words
A unit dosage form according to claim 1 in which said alkaline tablet has a thickness in the range of from about 0.210" to 0.225".
Claim 4
Dependent Claim
21 words
A unit dosage form according to claim 2 in which said tablet has the form of a spheroid or near spheroid.
Claim 5
Dependent Claim
34 words
A unit dosage form according to claim 2 in which the aspirin is present in said capsule at a level in the range of from about 400 mg. to about 500 mg. per capsule.
Claim 6
Dependent Claim
37 words
A unit dosage form according to claim 4 wherein the alkaline material contained in said capsule is between about 30% to about 100% by weight based on the total weight of the aspirin contained in the capsule.
Claim 7
Dependent Claim
24 words
A unit dosage form according to claims 1, 2, 3, 4 or 5 in which the alkaline tablet comprises a mixture of alkaline materials.
Claim 8
Dependent Claim
21 words
A unit dosage form according to claim 6 in which said mixture of alkaline materials comprises magnesium carbonate and calcium carbonate.
Claim 9
Dependent Claim
35 words
A unit dosage form according to claim 7 in which the ratio of calcium carbonate to magnesium carbonate on a weight basis present in said capsule is within the range of from 1:1 to 3:1.
Claim 10
Dependent Claim
22 words
A unit dosage form according to claim 1 in which at least one additional pharmaceutically active ingredient is contained in said capsule.
Claim 11
Dependent Claim
19 words
A unit dosage form according to claim 9 in which said additional pharmaceutically active ingredient is an additional analgesic.
Claim 12
Dependent Claim
18 words
A unit dosage form according to claim 9 in which said additional pharmaceutically active ingredient is a decongestant.
Claim 13
Dependent Claim
18 words
A unit dosage form according to claim 9 in which said additional pharmaceutically active ingredient is an antihistamine.
Claim 14
Dependent Claim
22 words
A unit dosage form according to claim 9 in which said additional active ingredients is a mixture of decongestant, antihistamine and antitussive.
References Cited (Backward Citations)
FR808949A
Cited
US2224256A
Cited
US2447396A
Cited
US2698332A
Cited
US2918485A
Cited
US2889248A
Cited
US2801951A
Cited
US2888382A
Cited
US2990328A
Cited
US3019169A
Cited
US3323992A
Cited
GB1204580A
Cited
US4167558A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-10-12 | 1985-04-13 | 1985-10-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-10-12 | 1989-04-13 | 1989-10-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-10-12 | 1993-04-13 | 1993-10-13 | $7700.00 | Window Closed / Lapsed |