US4291025A
Expired / Lapsed
US
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Agar gel topical dressing
Assignee: LACLEDE PROFESSIONAL PRODUCTS Inc A CORP OF NY
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Filing: 1980-04-11
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Granted: 1981-09-22
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Expires: 2000-04-11
Abstract
Abstract An agar gel topical dressing for coating a burn area or other area of skin impairment is prepared by heating and agitating a mixture of agar, diethylene glycol and water to solubilize the agar. The resulting solution, upon cooling to its gelation temperature, is converted to a thermally reversible agar gel. Application of the agar gel as a burn coating is undertaken by heating the gel to obtain a sol, applying the sol to the burn area at a tissue compatible temperature, and allowing the sol to cool and set in the form of a gel.
Inventors
- 👤 Michael A. Pellico
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:22
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61L; A61L26/00; A61L26/0009; A61L26/0023; A61L26/0061; A61L26/008; Y; Y10; Y10S; Y10S424/00; Y10S424/13; Y10S602/00; Y10S602/90
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
27 words
An agar gel topical dressing, which comprises about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.%.
Claim 2
Dependent Claim
27 words
An agar gel topical dressing, which comprises about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.%.
Claim 3
Dependent Claim
32 words
The dressing of claim 1 wherein the concentration of agar is from about 8 to about 10 wt.% and the concentration of diethylene glycol is from about 40 to about 55 wt.%.
Claim 4
Dependent Claim
28 words
The dressing of claim 1 which includes a gel strengthening agent selected from the group consisting of sodium borate, potassium borate, potassium sulfate, zinc sulfate and mixtures thereof.
Claim 5
Independent Claim
69 words
A method for preparing a thermally reversible, agar gel topical dressing having a gelation temperature from about 24° to abour 49° C, which comprises heating and agitating an admixture containing about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.% to solubilize the agar and allowing the resulting solution to cool and set in the form of a gel.
Claim 6
Independent Claim
69 words
A method for preparing a thermally reversible, agar gel topical dressing having a gelation temperature from about 24° to abour 49° C, which comprises heating and agitating an admixture containing about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.% to solubilize the agar and allowing the resulting solution to cool and set in the form of a gel.
Claim 7
Dependent Claim
27 words
The method of claim 4 wherein the admixture contains from about 8 to about 10 wt.% agar and from about 40 to about 55 wt.% diethylene glycol.
Claim 8
Dependent Claim
30 words
The method of claim 4 wherein the admixture includes a gel strengthening agent selected from the group consisting of sodium borate, potassium borate, potassium sulfate, zinc sulfate and mixtures thereof.
Claim 9
Dependent Claim
26 words
The method of claim 4 wherein the mixture is heated and agitated at a temperature between about 90° and about 104° C. to solubilize the agar.
Claim 10
Independent Claim
102 words
A method for applying an agar gel topical dressing to a burn area or other area of skin impairment, which comprises: (a) heating a thermally reversible, agar gel topical dressing containing about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.% to obtain a sol, said sol having a gelation temperature from about 24° to about 49° C.; (b) applying the sol at a tissue compatible temperature to the burn area or other area of skin impairment; and (c) allowing the sol to cool and set in the form of a gel.
Claim 11
Independent Claim
102 words
A method for applying an agar gel topical dressing to a burn area or other area of skin impairment, which comprises: (a) heating a thermally reversible, agar gel topical dressing containing about 5 to about 12 wt.% agar, about 20 to about 75 wt.% diethylene glycol and water to 100 wt.% to obtain a sol, said sol having a gelation temperature from about 24° to about 49° C.; (b) applying the sol at a tissue compatible temperature to the burn area or other area of skin impairment; and (c) allowing the sol to cool and set in the form of a gel.
Claim 12
Dependent Claim
27 words
The method of claim 8 wherein the dressing contains from about 8 to about 10 wt.% agar and from about 40 to about 55 wt.% diethylene glycol.
Claim 13
Dependent Claim
33 words
The method of claim 8 wherein the agar gel topical dressing includes a gel strengthening agent selected from the group consisting of sodium borate, potassium borate, potassium sulfate, zinc sulfate and mixtures thereof.
Claim 14
Dependent Claim
37 words
The method of claim 8 wherein the agar gel topical dressing is heated to and maintained at a temperature from about 88° to about 93° C. to convert the topical dressing from a gel to a sol.
Claim 15
Dependent Claim
26 words
The method of claim 8 wherein the sol is applied to a wide mesh support grid overlying the burn area or other area of skin impairment.
Claim 16
Dependent Claim
32 words
The method of claim 8 wherein the sol is applied to the burn area or other area of skin impairment at a temperature above its gelation point and below about 51° C.
References Cited (Backward Citations)
US4112121A
Cited
US4186190A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-21 | 1985-03-23 | 1985-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-21 | 1989-03-23 | 1989-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-21 | 1993-03-23 | 1993-09-22 | $7700.00 | Window Closed / Lapsed |