US4291020A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Inactivation of non-A, non-B hepatitis agent
Assignee: United States Department of Health and Human Services
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Filing: 1980-05-16
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Granted: 1981-09-22
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Expires: 2000-05-16
Abstract
Abstract This invention relates to a method of inactivating a non-A, non-B hepatitis agent by means of formalin utilized in extended treatment. The range of formalin treatment utilizes a concentration of 1:1,000-1:10,000, preferred 1:1,000, and the duration of treatment is from 24-120 hours at any temperature with a preferred 96 hours (4 days) at 37 DEG +/-4 DEG C. This formalin-treated or otherwise inactivated agent, or portions of the agent, may be later used to produce a vaccine against non-A, non-B hepatitis.
Inventors
- 👤 Edward Tabor
- 👤 Robert J. Gerety
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 15:12
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/12; A61K39/29; A61K2039/51; A61K2039/525; A61K2039/5252; C; C12; C12N; C12N2770/00; C12N2770/00011; C12N2770/24011; C12N2770/24211; C12N2770/24234
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
26 words
A method of treating an agent of human non-A, non-B hepatitis virus with formalin at a concentration of 1:1,000-1:10,000 for 24-120 hours to inactivate said agent.
Claim 2
Independent Claim
26 words
A method of treating an agent of human non-A, non-B hepatitis virus with formalin at a concentration of 1:1,000-1:10,000 for 24-120 hours to inactivate said agent.
Claim 3
Dependent Claim
20 words
The method of claim 1 wherein lack of further infectivity of said agent is demonstrated by inoculation in a human.
Claim 4
Dependent Claim
12 words
The method of claim 2 wherein the inoculation is in a chimpanzee.
Claim 5
Dependent Claim
21 words
The method of claim 1 wherein formalin is used at a concentration of 1:1,000 for about 96 hours at 37°±4° C.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-21 | 1985-03-23 | 1985-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-21 | 1989-03-23 | 1989-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-21 | 1993-03-23 | 1993-09-22 | $7700.00 | Window Closed / Lapsed |