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US4290773A Expired / Lapsed US ⏱️ 0.0 years remaining

Stabilization of benzidine-type indicators with various enhancers

Assignee: Bayer Corp
•
Filing: 1979-11-13
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Granted: 1981-09-22
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Expires: 1999-11-13
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Abstract

Abstract An improved composition, device and method, whereby enhanced sensitivity is achieved in detecting test sample constituents such as glucose and blood. The improvement resides in the use of a broad range of compounds as enhancers for benzidine-type indicators. The enhancer tends to stabilize the blue colorform of such indicators.

Inventors

  • 👤 Thomas A. Magers
  • 👤 David L. Tabb

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 02:41
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/54; C12Q1/26; C12Q1/28; C12Q2326/00; C12Q2326/10; C12Q2326/12; C12Q2326/14; Y; Y10; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 59 words
In a composition for detecting the presence of a constituent in a test sample, said composition comprising a benzidine-type indicator, the improvement wherein said composition additionally comprises an enhancer compound have the structure ##STR5## wherein X is OH, CN, NO 2 , CHO, SO 3 R' or NRCOR'; R is lower alkyl; and R' is H or lower alkyl.
Claim 2
Dependent Claim 59 words
In a composition for detecting the presence of a constituent in a test sample, said composition comprising a benzidine-type indicator, the improvement wherein said composition additionally comprises an enhancer compound have the structure ##STR5## wherein X is OH, CN, NO 2 , CHO, SO 3 R' or NRCOR'; R is lower alkyl; and R' is H or lower alkyl.
Claim 3
Dependent Claim 14 words
The improved composition of claim 1 wherein said enhancer is phenol, nitrobenzene or benzonitrile.
Claim 4
Dependent Claim 30 words
A test device for determining the presence of a constituent in a test sample, said device comprising a carrier matrix incorporated with the improved composition of claim 1 or 2.
Claim 5
Dependent Claim 34 words
A method for determining the presence of a constituent in a test sample, said method comprising contacting said test sample with the improved composition of claim 1 or 2, and observing a detectable response.
Claim 6
Dependent Claim 34 words
A method for determining the presence of a constituent in a test sample, said method comprising contacting said test sample with the device of claim 3, and observing a detectable response for said device.

References Cited (Backward Citations)

US3290228A Cited
US4089747A Cited
US4071321A Cited
US4148611A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-09-21 1985-03-23 1985-09-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-09-21 1989-03-23 1989-09-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-09-21 1993-03-23 1993-09-22 $7700.00 Window Closed / Lapsed

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