US4289648A
Expired / Lapsed
US
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Blood gas controls composition, method and apparatus
Assignee: Ortho Clinical Diagnostics Inc
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Filing: 1979-03-20
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Granted: 1981-09-15
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Expires: 1999-03-20
Abstract
Abstract A hermetically sealed ampoule containing blood gas control fluid is provided wherein the fluid occupies the entire ampoule with no appreciable head space. The ampoule is provided with a plunger-like seal adapted to be directed against the contents of the ampoule and a pierceable seal through which may extend a hollow needle to act as a conduit for the contents upon expulsion from the ampoule. A syringe is also provided for expelling the contents from the ampoule.
Inventors
- 👤 Michael K. Hoskins
- 👤 Gary D. Christiansen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:08
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/05; A61J1/06; A61J1/062; G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/4925; G01N33/50; G01N33/96; G01N2496/00; G01N2496/25; G01N2496/30; G01N2496/70; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/102499
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
93 words
A device comprising a hermetically sealed, gas-impermeable container containing a blood gas control liquid and having essentially no bubbles or gaseous head space, said liquid consists essentially of a. dissolved carbon dioxide in equilibrium with a water soluble carbonate or bicarbonate salt source in solution b. dissolved oxygen in equilibrium with a water soluble or water suspendible peroxide source in solution c. a water-soluble pH butter d. water e. said liquid having a pH of 7.0-7.7, a pO 2 of from 30-170 mm. Hg, and a pCO 2 of from 10-80 mm. Hg.
Claim 2
Independent Claim
93 words
A device comprising a hermetically sealed, gas-impermeable container containing a blood gas control liquid and having essentially no bubbles or gaseous head space, said liquid consists essentially of a. dissolved carbon dioxide in equilibrium with a water soluble carbonate or bicarbonate salt source in solution b. dissolved oxygen in equilibrium with a water soluble or water suspendible peroxide source in solution c. a water-soluble pH butter d. water e. said liquid having a pH of 7.0-7.7, a pO 2 of from 30-170 mm. Hg, and a pCO 2 of from 10-80 mm. Hg.
Claim 3
Dependent Claim
14 words
The device of claim 1 wherein the source of carbon dioxide is a bicarbonate.
Claim 4
Dependent Claim
23 words
The device of claim 1 wherein there is additionally present sodium chloride in a concentration of from 1.5 to 2.0 gms. per liter.
Claim 5
Dependent Claim
20 words
The device of claim 3 wherein the buffer comprises one or more of alkali metal mono or di-basic phosphate salts.
Claim 6
Dependent Claim
20 words
The device of claim 3 wherein the source of CO 2 is an alkali metal or alkaline earth metal bicarbonate.
Claim 7
Dependent Claim
13 words
The device of claim 3 wherein the source of oxygen is hydrogen peroxide.
Claim 8
Dependent Claim
31 words
The device of claim 4 wherein the phosphate salts are selected from one or more of sodium monobasic phosphate, sodium di-basic phosphate, potassium monobasic phosphate, potassium di-basic phosphate and mixtures thereof.
Claim 9
Dependent Claim
20 words
The device of claim 1 wherein the carbon dioxide source is sodium bicarbonate and the oxygen source is hydrogen peroxide.
Claim 10
Dependent Claim
23 words
The device of claim 7 wherein said container is essentially clear to the transmission of light thereby permitting visual inspection of said composition.
Claim 11
Dependent Claim
78 words
A blood gas control composition which consists essentially of (a) water (b) dissolved CO 2 in equilibrium with a water-soluble carbonate or bicarbonate salt source in solution (c) dissolved oxygen in equilibrium with a water soluble or water suspendible peroxide source in solution (d) a water soluble pH buffer (e) said composition having a pH of 7.0-7.7, a pO 2 of from 30 to 170 mm Hg, and a pCO 2 of from 10 to 80 mm Hg
Claim 12
Dependent Claim
78 words
A blood gas control composition which consists essentially of (a) water (b) dissolved CO 2 in equilibrium with a water-soluble carbonate or bicarbonate salt source in solution (c) dissolved oxygen in equilibrium with a water soluble or water suspendible peroxide source in solution (d) a water soluble pH buffer (e) said composition having a pH of 7.0-7.7, a pO 2 of from 30 to 170 mm Hg, and a pCO 2 of from 10 to 80 mm Hg
Claim 13
Dependent Claim
29 words
The composition of claim 10 wherein the source of oxygen is hydrogen peroxide and the dissolved CO 2 is an alkali metal or alkaline earth metal carbonate or bicarbonate.
Claim 14
Dependent Claim
20 words
The composition of claim 11 wherein the buffer comprises one or more of alkali metal mono and di-basic phosphate salts.
Claim 15
Dependent Claim
16 words
The composition of claim 10 wherein the composition has a pH of from 7.1 to 7.6.
Claim 16
Dependent Claim
29 words
The composition of claim 10 additionally containing an agent to increase the surface tension of the composition and retard absorption or diffusion of gases from the composition during handling.
Claim 17
Dependent Claim
12 words
The composition of claim 14 wherein said agent is a polyethylene glycol.
Claim 18
Dependent Claim
20 words
The composition of claim 10 additionally containing sodium chloride in a concentration of from 1.5 to 2.0 gms. per liter.
Claim 19
Dependent Claim
32 words
The device of claim 1 wherein the liquid additionally contains an agent to increase the surface tension of the liquid and retard absorption or diffusion of gases from the liquid during handling.
Claim 20
Dependent Claim
12 words
The device of claim 17 wherein said agent is a polyethylene glycol.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-14 | 1985-03-16 | 1985-09-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-14 | 1989-03-16 | 1989-09-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-14 | 1993-03-16 | 1993-09-15 | $7700.00 | Window Closed / Lapsed |