US4284537A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Conjugate of streptococcal M protein peptide vaccine
Assignee: United States Department of Health and Human Services
•
Filing: 1980-07-03
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Granted: 1981-08-18
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Expires: 2000-07-03
Abstract
Abstract Certain peptide fragments of streptococcal M protein named CB6 and CB7 have been linked to a protein carrier which is polylysine. The conjugate has proved immunogenic in rabbits producing protective antibodies against the whole group A streptococcus.
Inventors
- 👤 Edwin H. Beachey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:19
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/12; C07K16/1267; C07K16/1275; A; A61; A61K; A61K39/00; A61K39/385; A61K47/00; A61K47/50; A61K47/51; A61K47/62; A61K47/64; A61K47/645; C07K14/00; C07K14/195; C07K14/315; A61K2039/60; A61K2039/6093; A61K38/00; C07K2317/00; C07K2317/70; C07K2317/77; Y; Y10; Y10S; Y10S524/00; Y10S524/90
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
20 words
The conjugation of M24 protein particle CB6 or CB7 with polylysine which produces a conjugation antisera against animal streptococcus infection.
Claim 2
Dependent Claim
20 words
The conjugation of M24 protein particle CB6 or CB7 with polylysine which produces a conjugation antisera against animal streptococcus infection.
Claim 3
Dependent Claim
14 words
The conjugation according to claim 1 wherein CB6 is utilized as an immunogenic agent.
Claim 4
Dependent Claim
14 words
The conjugation according to claim 1 wherein CB7 is utilized as an immunogenic agent.
Claim 5
Dependent Claim
14 words
A process of producing a conjugate of CB6 or CB7 or both with polylysine.
Claim 6
Dependent Claim
14 words
A process of producing a conjugate of CB6 or CB7 or both with polylysine.
Claim 7
Dependent Claim
21 words
The process according to claim 4 wherein additionally the reactants were subjected to a dialysis for an extended period of time.
Claim 8
Dependent Claim
14 words
The process according to claim 5 wherein the reactants were stirred for 18 hours.
References Cited (Backward Citations)
US3963691A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-08-17 | 1985-02-16 | 1985-08-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-08-17 | 1989-02-16 | 1989-08-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-08-17 | 1993-02-16 | 1993-08-18 | $7700.00 | Window Closed / Lapsed |