Antihistaminic 11-(4-piperidylidene)-5H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridines

Claim 1

A compound of the formula ##STR2## wherein the dotted line represents an optional double bond; X is hydrogen or halo; and wherein Y is --COOR or SO 2 R; with the proviso that when Y is --COOR, R is C 1 to C 12 alkyl, substituted C 1 to C 12 alkyl, phenyl, substituted phenyl, C 7 to C 12 phenylalkyl, C 7 to C 12 phenylalkyl wherein the phenyl moiety is substituted or R is -2,-3, or -4 piperidyl or N-substituted piperidyl wherein the substituents on said substituted C 1 to C 12 alkyl are selected from amino or substituted amino and the substituents on said substituted amino are selected from C 1 to C 6 alkyl, the substituents on said substituted phenyl and on said substituted phenyl moiety of the C 7 to C 12 phenylalkyl are selected from C 1 to C 6 alkyl and halo, and the substituent on said N-substituted piperidyl is C 1 to C 4 alkyl; and with the proviso that when Y is SO 2 R, R is C 1 to C 12 alkyl, phenyl, substituted phenyl, C 7 to C 12 phenylalkyl, C 7 to C 12 phenylalkyl wherein the phenyl moiety is substituted, wherein the substituents on said substituted phenyl and said substituted phenyl moiety of the C 7 to C 12 phenylalkyl are selected from C 1 to C 6 alkyl and halo.

Claim 19

A method of effecting an anti-allergic response in an animal comprising administering to the animal an effective amount of a compound as claimed in any one of claims 1 to 11.