US4280996A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fat emulsion for intravenous injection
Assignee: Tanabe Pharma Corp
•
Filing: 1979-09-13
•
Granted: 1981-07-28
•
Expires: 1999-09-13
Abstract
Abstract A stable fat emulsion having low side effects, which is suitable as nutritive infusion fluid for intravenous injection, is provided. The emulsion contains 5-50 (W/V) % of soybean oil, yolk phospholipids in a weight ratio to the soybean oil of 1/4-1/25, 0.01-0.30 (W/V) % of a fatty acid or salt thereof having 12-20 carbon atoms and the balance of water.
Inventors
- 👤 Hiroyuki Okamoto
- 👤 Yoshio Tsuda
- 👤 Kazumasa Yokoyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 13:44
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0029; A61K31/00; A61K31/66; A61K31/683; A61K31/685; A61K36/00; A61K36/18; A61K36/185; A61K36/48; A61P; A61P3/00; A61P3/06
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
74 words
A fat emulsion suitable for intravenous injection comprising 5 to 50 (w/v)% of soybean oil, yolk phospholipids in a weight ratio of the soybean oil of 1/4 to 1/25, glycerol or glucose as an isotonic agent, the diameter of the emulsified particles being 0.1μ or less, water, 0.01 to 0.30 (w/v)% of a fatty acid having 12 to 20 carbon atoms or a pharmaceutically acceptable salt thereof and 0.005 to 0.50 (w/v)% of cholesterol.
Claim 2
Dependent Claim
74 words
A fat emulsion suitable for intravenous injection comprising 5 to 50 (w/v)% of soybean oil, yolk phospholipids in a weight ratio of the soybean oil of 1/4 to 1/25, glycerol or glucose as an isotonic agent, the diameter of the emulsified particles being 0.1μ or less, water, 0.01 to 0.30 (w/v)% of a fatty acid having 12 to 20 carbon atoms or a pharmaceutically acceptable salt thereof and 0.005 to 0.50 (w/v)% of cholesterol.
Claim 3
Dependent Claim
23 words
An emulsion according to claim 1, wherein the amount of the fatty acid or pharmaceutically acceptable salt thereof is 0.04 to 0.07 (W/V)%.
Claim 4
Dependent Claim
38 words
An emulsion according to 1 wherein the fatty acid is stearic acid, oleic acid, linoleic acid, palmitic acid or linolenic acid and the amount of the fatty acid or pharmaceutically acceptable salt thereof is 0.04 to 0.07 (w/v)%.
Claim 5
Dependent Claim
38 words
An emulsion according to 1 wherein the fatty acid is stearic acid, oleic acid, linoleic acid, palmitic acid or linolenic acid and the amount of the fatty acid or pharmaceutically acceptable salt thereof is 0.04 to 0.07 (w/v)%.
Claim 6
Dependent Claim
32 words
An emulsion according to claim 1 which is characterized by being sufficiently stable after storage at 4° C. for 24 months that the emulsified particles have a diameter of not over 0.11±0.03μ.
References Cited (Backward Citations)
CA615342A
Cited
US1939166A
Cited
US2185969A
Cited
US3004892A
Cited
CA725596A
Cited
FR8014M
Cited
US4089801A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-07-27 | 1985-01-26 | 1985-07-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-07-27 | 1989-01-26 | 1989-07-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-07-27 | 1993-01-26 | 1993-07-28 | $7700.00 | Window Closed / Lapsed |