US4277461A
Expired / Lapsed
US
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Vaginal contraceptive
Assignee: Individual
•
Filing: 1979-12-20
•
Granted: 1981-07-07
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Expires: 1999-12-20
Abstract
Abstract The contraceptive consists of a spermicidal active substance of the formula RCONH-(CH2CH2O)n-H, in which R denotes a C5-C19-alkyl or -alkenyl radical and n has a value of 3 to 20, a mixture of an alkali metal bicarbonate and a water-soluble, solid, anhydrous mono- or poly-carboxylic acid having 2 to 6 carbon atoms, in a stoichiometric ratio, as a foam generator, and a polyethylene glycol, or mixture of polyethylene glycols, which melts at body temperature.
Inventors
- 👤 Peter W. Lucker
- 👤 Nikolaus Wetzelsberger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 19:48
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0034; A61K31/00; A61K31/16; Y; Y10; Y10S; Y10S424/00; Y10S424/14; Y10S424/15
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
124 words
A contraceptive for vaginal use, consisting essentially of a spermicidal active substance of the formula RCONH--(CH.sub.2 CH.sub.2 O).sub.n --H in which R denotes an alkyl or alkenyl radical having from 5 to 19 carbon atoms and n has a value of from 3 to 20, in an amount which is adequate for reliable contraception, a foam generator consisting of a mixture of an alkali metal bicarbonate and a water-soluble, solid, anhydrous acid selected from the group consisting of mono- and poly-carboxylic acids having from 2 to 6 carbon atoms, in a stoichiometric ratio, in an amount which just suffices to produce foam, and a water-soluble excipient selected from the group consisting of polyethylene glycols and mixtures of polyethylene glycols, which melts at body temperature.
Claim 2
Dependent Claim
124 words
A contraceptive for vaginal use, consisting essentially of a spermicidal active substance of the formula RCONH--(CH.sub.2 CH.sub.2 O).sub.n --H in which R denotes an alkyl or alkenyl radical having from 5 to 19 carbon atoms and n has a value of from 3 to 20, in an amount which is adequate for reliable contraception, a foam generator consisting of a mixture of an alkali metal bicarbonate and a water-soluble, solid, anhydrous acid selected from the group consisting of mono- and poly-carboxylic acids having from 2 to 6 carbon atoms, in a stoichiometric ratio, in an amount which just suffices to produce foam, and a water-soluble excipient selected from the group consisting of polyethylene glycols and mixtures of polyethylene glycols, which melts at body temperature.
Claim 3
Dependent Claim
25 words
A contraceptive according to claim 1, wherein, in the above formula, R denotes an alkyl or alkenyl radical having from 11 to 19 carbon atoms.
Claim 4
Dependent Claim
21 words
A contraceptive according to claim 1, wherein, in the above formula, n has an average value of from 4 to 12.
Claim 5
Dependent Claim
36 words
A contraceptive according to claim 1, wherein, in the above formula, R denotes an alkyl or alkenyl radical having from 11 to 19 carbon atoms and n has an average value of from 4 to 12.
Claim 6
Dependent Claim
33 words
A contraceptive according to claim 2, wherein, in the above formula, the RCO-group denotes the lauryl, myristyl, palmityl, stearyl, arachinyl or oleyl radical or a mixture of two or more of these radicals.
Claim 7
Dependent Claim
40 words
A contraceptive according to claim 5, wherein the RCO-group denotes the lauryl, myristyl, palmityl, stearyl, arachinyl or oleyl radical or a mixture of two or more of these radicals and n has an average value of from 4 to 12.
Claim 8
Dependent Claim
31 words
A contraceptive according to claim 6, wherein the RCO-group corresponds to the carboxylic acid mixture of the acid hydrolysis product of coconut oil and n has an average value of 6.
Claim 9
Dependent Claim
21 words
A contraceptive according to claim 6, wherein the RCO-group denotes the oleyl radical and n has an average value of 8.
Claim 10
Dependent Claim
21 words
A contraceptive according to claim 6, wherein the RCO-group denotes the lauryl radical and n has an average value of 9.
Claim 11
Dependent Claim
22 words
A contraceptive according to claim 1, wherein the mono- or poly-carboxylic acid consists of a hydroxycarboxylic acid or of an aminodicarboxylic acid.
Claim 12
Dependent Claim
40 words
A contraceptive according to claim 1, wherein the alkali metal bicarbonate consists of sodium bicarbonate and the water-soluble, solid, anhydrous acid consists of tartaric acid, said sodium bicarbonate and said tartaric acid being in a molar ratio of about 2:1.
Claim 13
Dependent Claim
61 words
A contraceptive according to claim 11, wherein the spermicidal active substance is present in a proportion by weight of about 2 to 10%, sodium bicarbonate and tartaric acid are present in a proportion by weight of about 8 to 25% and the polyethylene glycol or mixture of polyethylene glycols is present in a proportion by weight of about 65 to 90%.
Claim 14
Dependent Claim
18 words
The use of the contraceptive according to claim 1 in the form of a suppository for preventing pregnancy.
Claim 15
Dependent Claim
31 words
A contraceptive according to claim 10, wherein the mono- or poly-carboxylic acid consists of glycolic acid, l-lactic acid, malic acid, tartaric acid, citric acid, glutamic acid, hydroxyglutamic acid or α-aminoadipic acid.
References Cited (Backward Citations)
US3883661A
Cited
US4187286A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-07-06 | 1985-01-05 | 1985-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-07-06 | 1989-01-05 | 1989-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-07-06 | 1993-01-05 | 1993-07-07 | $7700.00 | Window Closed / Lapsed |