US4273709A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the preparation of thienamycin and intermediates
Assignee: MECK & Co Inc
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Filing: 1979-07-23
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Granted: 1981-06-16
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Expires: 1999-07-23
Abstract
Abstract Disclosed is a process for the total synthesis of thienamycin from 4-allylazetidinone (IIIa) via ##STR1## L-aspartic acid (III): ##STR2## R═H, blocking group or salt cation.
Inventors
- 👤 Burton G. Christensen
- 👤 Ronald W. Ratcliffe
- 👤 Thomas N. Salzmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 16:17
CPC Classifications
C; C07; C07D; C07D477/00; C07D477/02; C07D477/04; C07D205/00; C07D205/02; C07D205/06; C07D205/08; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/10
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
22 words
The compound of the formula ##STR22## wherein R 1 is triloweralkylsilyl, wherein the alkyl moieties have from 1 to 6 carbon atoms.
Claim 2
Dependent Claim
22 words
The compound of the formula ##STR22## wherein R 1 is triloweralkylsilyl, wherein the alkyl moieties have from 1 to 6 carbon atoms.
Claim 3
Dependent Claim
27 words
The compound selected from the group consisting of ##STR23## wherein R 1 is hydrogen or triloweralkylsilyl, wherein the alkyl moieties individually have 1 to 6 carbon atoms.
Claim 4
Dependent Claim
27 words
The compound selected from the group consisting of ##STR23## wherein R 1 is hydrogen or triloweralkylsilyl, wherein the alkyl moieties individually have 1 to 6 carbon atoms.
Claim 5
Dependent Claim
21 words
A compound of the formula: ##STR24## wherein R 1 is selected from the group consisting of t-butyldimethylsilyl, t-butyldiphenylsilyl, triphenysilyl and isopropyldimethylsilyl.
Claim 6
Dependent Claim
21 words
A compound of the formula: ##STR24## wherein R 1 is selected from the group consisting of t-butyldimethylsilyl, t-butyldiphenylsilyl, triphenysilyl and isopropyldimethylsilyl.
Claim 7
Dependent Claim
25 words
A compound selected from the group consisting of: ##STR25## wherein R 1 is selected from the group consisting of hydrogen, t-butyldimethylsilyl, t-butyldiphenylsilyl, triphenylsilyl and isopropyldimethylsilyl.
Claim 8
Dependent Claim
25 words
A compound selected from the group consisting of: ##STR25## wherein R 1 is selected from the group consisting of hydrogen, t-butyldimethylsilyl, t-butyldiphenylsilyl, triphenylsilyl and isopropyldimethylsilyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-06-15 | 1984-12-15 | 1985-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-06-15 | 1988-12-15 | 1989-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-06-15 | 1992-12-15 | 1993-06-16 | $7700.00 | Window Closed / Lapsed |