US4272528A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Phosphonoacetyl aminoacids
Assignee: Abbott Laboratories
•
Filing: 1980-08-14
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Granted: 1981-06-09
•
Expires: 2000-08-14
Abstract
Abstract Certain phosphonoacetyl aminoacids have been found to be useful antiviral agents suitable to combat herpes virus infection of various types.
Inventors
- 👤 Anne M. Von Esch
- 👤 Alford M. Thomas
- 👤 John S. Fairgrieve
- 👤 John H. Seely
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 00:05
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/38; C07F9/3804; C07F9/3808
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
39 words
A compund of the formula ##STR3## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR4## and the nontoxic salts thereof.
Claim 2
Dependent Claim
39 words
A compund of the formula ##STR3## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR4## and the nontoxic salts thereof.
Claim 3
Dependent Claim
11 words
The compound of claim 1 wherein X is CH 2 .
Claim 4
Dependent Claim
11 words
The compound of claim 1 wherein X is >CHCH 3 .
Claim 5
Dependent Claim
13 words
The compound of claim 1 wherein X is --CH 2 CH 2 --.
Claim 6
Dependent Claim
9 words
The compound of claim 1 wherein X is ##STR5##
Claim 7
Dependent Claim
15 words
The compound of claim 1 wherein X is >CHCH 2 CH(CH 3 ) 2 .
Claim 8
Dependent Claim
13 words
The compound of claim 1 wherein X is >CHCH 2 CONH 2 .
Claim 9
Dependent Claim
58 words
A topical pharmaceutical composition for treating herpes virus infections in warm-blooded animals comprising a compound of the formula: ##STR6## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR7## and the nontoxic salts thereof, together with a topically acceptable diluent.
Claim 10
Dependent Claim
58 words
A topical pharmaceutical composition for treating herpes virus infections in warm-blooded animals comprising a compound of the formula: ##STR6## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR7## and the nontoxic salts thereof, together with a topically acceptable diluent.
Claim 11
Dependent Claim
11 words
The composition of claim 8 wherein X is --CH 2 .
Claim 12
Dependent Claim
11 words
The composition of claim 8 wherein X is >CHCH 3 .
Claim 13
Dependent Claim
14 words
The composition of claim 8 wherein X is --CH 2 CH 2 31 .
Claim 14
Dependent Claim
9 words
The composition of claim 8 wherein X is ##STR8##
Claim 15
Dependent Claim
15 words
The composition of claim 8 wherein X is >CHCH 2 CH(CH 3 ) 2 .
Claim 16
Dependent Claim
13 words
The composition of claim 8 wherein X is >CHCH 2 CONH 2 .
Claim 17
Independent Claim
70 words
A method for treating herpes simplex virus infection in a warm-blooded animal which comprises administering to an animal so infected, an effective amount to combat said virus of a composition containing a compound of the formula ##STR9## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR10## and the nontoxic salts thereof.
Claim 18
Independent Claim
70 words
A method for treating herpes simplex virus infection in a warm-blooded animal which comprises administering to an animal so infected, an effective amount to combat said virus of a composition containing a compound of the formula ##STR9## wherein X stands for >CHCH 3 , --CH 2 --, --CH 2 CH 2 --, >CHCH 2 CH(CH 3 ) 2 , >CHCH 2 CONH 2 or ##STR10## and the nontoxic salts thereof.
Claim 19
Dependent Claim
11 words
The method of claim 15 wherein X is --CH 2 --.
Claim 20
Dependent Claim
11 words
The method of claim 11 wherein X is >CHCH 3 .
Claim 21
Dependent Claim
13 words
The method of claim 11 wherein X is --CH 2 CH 2 .
Claim 22
Dependent Claim
9 words
The method of claim 11 wherein X is ##STR11##
Claim 23
Dependent Claim
15 words
The method of claim 15 wherein X is >CHCH 2 CH(CH 3 ) 2 .
Claim 24
Dependent Claim
13 words
The method of claim 15 wherein X is >CHCH 2 CONH 2 .
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-06-08 | 1984-12-08 | 1985-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-06-08 | 1988-12-08 | 1989-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-06-08 | 1992-12-08 | 1993-06-09 | $7700.00 | Window Closed / Lapsed |