US4271083A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6-Hydroxy-1,4-benzoquinone compounds
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1978-11-15
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Granted: 1981-06-02
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Expires: 1998-11-15
Abstract
Abstract Novel compounds of the formula ##STR1## wherein R represents lower alkyl or lower alkoxy, A represents --CH 2 --, --CO-- or ##STR2## n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.
Inventors
- 👤 Hiroshi Morimoto
- 👤 Isuke Imada
- 👤 Masazumi Watanabe
- 👤 Mitsuru Kawada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 09:52
CPC Classifications
C; C07; C07C; C07C66/00; C07C37/00; C07C37/001; C07C37/002; C07C37/50; C07C39/00; C07C39/02; C07C39/11; C07C45/00; C07C45/51; C07C45/54; C07C45/61; C07C45/67; C07C45/673; C07C46/00; C07C46/02; C07C46/06; C07C49/00; C07C49/76; C07C49/82; C07C49/84; C07C50/00; C07C50/26; C07C50/28; C07C50/38; C07C59/00; C07C59/40; C07C59/42; C07C59/52; C07C59/58; C07C59/64; C07C59/76; C07C59/90; C07C65/00; C07C65/32; C07C65/40
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
44 words
A compound of the formula ##STR15## wherein R represents alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms, A represents --CH 2 --, --CO-- or ##STR16## and n represents an integer of 1 to 8, or its ester.
Claim 2
Dependent Claim
44 words
A compound of the formula ##STR15## wherein R represents alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms, A represents --CH 2 --, --CO-- or ##STR16## and n represents an integer of 1 to 8, or its ester.
Claim 3
Dependent Claim
13 words
A compound as claimed in claim 1, wherein A is --CH 2 --.
Claim 4
Dependent Claim
11 words
A compound as claimed in claim 1, wherein A is --CO--.
Claim 5
Dependent Claim
11 words
A compound as claimed in claim 1, wherein A is ##STR17##
Claim 6
Dependent Claim
12 words
The compound as claimed in claim 1, wherein the compound is 2,3,5-trimethyl-6-(6'-hydroxyhexyl)-1,4-benzoquinone.
Claim 7
Dependent Claim
12 words
The compound as claimed in claim 1, wherein the compound is 2,3-dimethoxy-5-methyl-6-(4'-hydroxybutyl)-1,4-benzoquinone.
Claim 8
Dependent Claim
12 words
The compound as claimed in claim 1, wherein the compound is 2,3,5-trimethyl-6-(6'-hydroxy-1'-oxohexyl)-1,4-benzoquinone.
Claim 9
Dependent Claim
12 words
The compound as claimed in claim 1, wherein the compound is 2,3,5-trimethyl-6-(1',6'-dihydroxyhexyl)-1,4-benzoquinone.
Claim 10
Dependent Claim
12 words
The compound as claimed in claim 1, wherein the compound is 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone.
Claim 11
Dependent Claim
94 words
A compound as claimed in claim 1, wherein the ester is an alkyl carboxylic acid ester in which the alkyl moiety of said alkyl carboxylic acid has 1-4 carbon atoms, an aryl carboxylic acid ester in which the aryl moiety of said aryl carboxylic acid has 6-7 carbon atoms, or an aralkyl carboxylic acid ester in which the aralkyl moiety of said aralkyl carboxylic acid has 7-8 carbon atoms, said alkyl, aryl and aralkyl moieties of said carboxylic acids being unsubstituted or substituted by at least one of sulfo, carboxyl, formyl, hydroxyl and amino.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-06-01 | 1984-12-01 | 1985-06-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-06-01 | 1988-12-01 | 1989-06-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-06-01 | 1992-12-01 | 1993-06-02 | $7700.00 | Window Closed / Lapsed |