Patent US5183531A successfully refreshed from Google Patents.
US4261884A
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Preparation of dehydropeptides
Assignee: Research Corp
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Filing: 1979-10-01
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Granted: 1981-04-14
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Expires: 1999-10-01
Abstract
Abstract A preparation of azlactones represented by the formula ##STR1## wherein R is a substituted or unsubstituted alkyl, aryl or nitrogen containing heterocyclic group, and R 1 is an N-blocked amino acid residue or peptide chain, and stereoisomers thereof, by oxidizing the corresponding saturated azlactone with a benzoquinone oxidizing agent in the presence of a base is disclosed. The unsaturated azlactones, some of which are novel, can be converted to dehydro peptides, which are useful as intermediates for preparing novel biologically active compounds, or themselves have biological activity.
Inventors
- 👤 Charles H. Stammer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 17:15
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/08; C07K5/0821; C07K5/0823; C07C; C07C321/00; C07K1/00; C07K1/006
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
5 words
The compound, aspartyldehydrophenylalanine methyl ester.
Claim 2
Dependent Claim
5 words
The compound, aspartyldehydrophenylalanine methyl ester.
Claim 3
Dependent Claim
5 words
The compound tyrosyl-D-alanyl-glycyl-dehydrophenylalanine methionine amide.
Claim 4
Dependent Claim
5 words
The compound tyrosyl-D-alanyl-glycyl-dehydrophenylalanine methionine amide.
Claim 5
Dependent Claim
3 words
The compound, arginyl-prolyl-prolyl-glycyl-dehydrophenylalanyl-seryl-prolyl-phenylalanyl-arginine.
Claim 6
Dependent Claim
3 words
The compound, arginyl-prolyl-prolyl-glycyl-dehydrophenylalanyl-seryl-prolyl-phenylalanyl-arginine.
Claim 7
Dependent Claim
6 words
The compound, N-carbobenzoxy-prolyl-dehydrophenylalanyl-histidyl-leucine, and its stereoisomers.
Claim 8
Dependent Claim
6 words
The compound, N-carbobenzoxy-prolyl-dehydrophenylalanyl-histidyl-leucine, and its stereoisomers.
Claim 9
Dependent Claim
5 words
The compound, leucyl-dehydrophenylalanyl-valyl-phenylalanine methyl ester.
Claim 10
Dependent Claim
5 words
The compound, leucyl-dehydrophenylalanyl-valyl-phenylalanine methyl ester.
Claim 11
Dependent Claim
5 words
The compound, N-t-butoxy carbonyl-D-alanyl-glycyl-dehydrophenylalanyl-methionine amide.
Claim 12
Dependent Claim
5 words
The compound, N-t-butoxy carbonyl-D-alanyl-glycyl-dehydrophenylalanyl-methionine amide.
Claim 13
Dependent Claim
5 words
The compound, tyrosyl-D-alanyl-glycyl-dehydrophenylalanyl-methionine amide acetate.
Claim 14
Dependent Claim
5 words
The compound, tyrosyl-D-alanyl-glycyl-dehydrophenylalanyl-methionine amide acetate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-04-13 | 1984-10-13 | 1985-04-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-04-13 | 1988-10-13 | 1989-04-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-04-13 | 1992-10-13 | 1993-04-14 | $7700.00 | Window Closed / Lapsed |