US4258059A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Amino-benzamides
Assignee: USV Pharmaceutical Corp
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Filing: 1979-06-21
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Granted: 1981-03-24
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Expires: 1999-06-21
Abstract
Abstract Compounds of the formula ##STR1## wherein: Ar and Ar' are independently alicyclic aryl or heterocyclic aryl groups; R 1 is a substituent replacing a hydrogen on the ring and is independently hydroxy, alkyl, alkoxy, halogen, nitro, amino, monoalkyl-amino, dialkyl-amino, sulfhydryl, alkylmercapto, sulfonamido, carboxy, carbalkoxy, or trihalomethyl; n is an integer from 0 to 5 inclusive; R 2 and R 3 are independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, or cycloalkyl-alkyl; and R 4 and R 5 are independently halogen or trihalomethyl, with the proviso that when both Ar and Ar' are phenyl and n is 0, both R 2 and R 3 are not hydrogen.
Inventors
- 👤 Joseph Auerbach
- 👤 Martin L. Kantor
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 09:27
CPC Classifications
C; C07; C07C; C07C243/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
65 words
A compound of the formula ##STR11## wherein R 1 is independently halogen, lower alkyl or trifluoromethyl, n is an integer from 0 to 2, R 2 is lower alkenyl, lower alkynyl, or cycloalkyl, and R 3 is hydrogen or lower alkyl wherein the alkyl, alkenyl, and alkynyl groups contain up to 6 carbon atoms and the cycloalkyl groups contain from 3 to 7 carbon atoms.
Claim 2
Dependent Claim
65 words
A compound of the formula ##STR11## wherein R 1 is independently halogen, lower alkyl or trifluoromethyl, n is an integer from 0 to 2, R 2 is lower alkenyl, lower alkynyl, or cycloalkyl, and R 3 is hydrogen or lower alkyl wherein the alkyl, alkenyl, and alkynyl groups contain up to 6 carbon atoms and the cycloalkyl groups contain from 3 to 7 carbon atoms.
Claim 3
Dependent Claim
10 words
A compound according to claim 1 wherein n is 0.
Claim 4
Dependent Claim
16 words
A compound according to claim 2 wherein R 2 is allyl and R 3 is hydrogen.
Claim 5
Dependent Claim
16 words
A compound according to claim 2 wherein R 2 is propargyl and R 3 is hydrogen.
Claim 6
Dependent Claim
16 words
A compound according to claim 2 wherein R 2 is cyclopropylmethyl and R 3 is hydrogen.
Claim 7
Dependent Claim
16 words
A compound according to claim 2 wherein R 2 is allyl and R 3 is methyl.
Claim 8
Dependent Claim
20 words
A compound according to claim 2 wherein R 2 is CH 3 C═C--CH 2 -- and R 3 is hydrogen.
Claim 9
Dependent Claim
22 words
A compound according to claim 2 wherein R 2 is (H 3 C)C═C(CH 3 )--CH 2 -- and R 3 is hydrogen.
Claim 10
Dependent Claim
21 words
A method of treating hypertension which comprises administering to animals having hypertension an effective dose of a compound of claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-23 | 1984-09-22 | 1985-03-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-23 | 1988-09-22 | 1989-03-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-23 | 1992-09-22 | 1993-03-24 | $7700.00 | Window Closed / Lapsed |