US4257939A
Expired / Lapsed
US
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Peptide derivative
Assignee: Ajinomoto Co Inc
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Filing: 1979-10-25
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Granted: 1981-03-24
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Expires: 1999-10-25
Abstract
Abstract A peptide derivative useful as substrates for determining enzymatic activities have the following formula ##STR1## wherein R 1 is a group selected from the group consisting of seryl, phenylalanyl-seryl, threonyl and leucyl-threonyl groups, and R 2 is ##STR2##
Inventors
- 👤 Shumpei Sakakibara
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:58
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/56; C07; C07D; C07D311/00; C07D311/02; C07D311/04; C07D311/06; C07D311/08; C07D311/16; C07K; C07K5/00; C07K5/04; C07K5/06; C07K5/06008; C07K5/06017; C07K5/06034; C07K5/06043; C07K5/0606; C07K5/08; C07K5/0802; C07K5/0804; C07K5/0808; C07K5/0812; C12Q1/34; C12Q1/37; C12Q2337/00; C12Q2337/10; C12Q2337/12; C12Q2337/20; C12Q2337/22; G; G01; G01N; G01N2333/00; G01N2333/90; G01N2333/914; G01N2333/948; G01N2333/95; G01N2333/964; G01N2333/96425; G01N2333/96427; G01N2333/9643; G01N2333/96433; G01N2333/96441; G01N2333/96452; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55; Y10; Y10S; Y10S530/00; Y10S530/802
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
30 words
A peptide derivative having the formula ##STR5## wherein R 1 is a group selected from the group consisting of seryl, phenylalanyl-seryl, threonyl and leucyl-threonyl groups, and R 2 is ##STR6##
Claim 2
Dependent Claim
30 words
A peptide derivative having the formula ##STR5## wherein R 1 is a group selected from the group consisting of seryl, phenylalanyl-seryl, threonyl and leucyl-threonyl groups, and R 2 is ##STR6##
Claim 3
Dependent Claim
19 words
The peptide derivative of claim 1 wherein the peptide derivative is in the form of an acid addition salt.
Claim 4
Dependent Claim
14 words
The peptide derivative of claim 1 wherein the terminal N.sup.α -amino group is protected.
Claim 5
Dependent Claim
12 words
The peptide derivative of claim 1 wherein the hydroxyl group is protected.
Claim 6
Dependent Claim
32 words
The peptide derivative of claim 3 wherein the protecting group for the terminal N.sup.α -amino group is a group selected from the group consisting of acyl, carbobenzoxy, tert-alkyloxycarbonyl, tosyl, and glutaryl groups.
Claim 7
Dependent Claim
24 words
The peptide derivative of claim 1 wherein the guanidino group of arginine which is found in the peptide derivative is protected by N-guanidino-protecting group.
References Cited (Backward Citations)
US3884896A
Cited
US4028318A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-23 | 1984-09-22 | 1985-03-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-23 | 1988-09-22 | 1989-03-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-23 | 1992-09-22 | 1993-03-24 | $7700.00 | Window Closed / Lapsed |