US4254239A
Expired / Lapsed
US
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Biodegradable vinylpyrrolidone polymers, their manufacture and use
Assignee: BASF SE
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Filing: 1978-12-28
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Granted: 1981-03-03
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Expires: 1998-12-28
Abstract
Abstract High molecular weight products based on N-vinylpyrrolidone, in which blocks of vinylpyrrolidone polymers or vinylpyrrolidone copolymers are linked by connecting units carrying ester, amide, urethane or urea groups, as a result of which these high molecular weight products are biodegradable and may be used as plasma substitutes, and the plasma substitutes thus obtained.
Inventors
- 👤 Ferdinand Straub
- 👤 Hans-Uwe Schenck
- 👤 Siegfried Lang
- 👤 Egon Brode
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:38
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/62; C08G18/6283; A; A61; A61K; A61K31/00; A61K31/74; A61K31/785; A61K31/787; A61K31/79; A61P; A61P7/00; A61P7/08; C08F; C08F8/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
117 words
A biodegradable vinylpyrrolidone polymer, usable as a blood plasma substitute, of the formula A--[B--A].sub.n --B--A where A is a vinylpyrrolidone polymer or copolymer block having a degree of polymerization of from 2 to 1,000, B is a short-chain connecting unit containing ester, amide, urea or urethane groups which groups are formed by (a) hydroxyl groups in A and carboxylic acid groups in B resulting in ester groups, (b) amino groups in A and carboxylic acid groups in B resulting in amide groups, (c) amino groups in A and isocyanate groups in B resulting in urea groups, (d) hydroxyl groups in A and isocyanate groups in B resulting in urethane groups and n is from 0 to 50.
Claim 2
Dependent Claim
117 words
A biodegradable vinylpyrrolidone polymer, usable as a blood plasma substitute, of the formula A--[B--A].sub.n --B--A where A is a vinylpyrrolidone polymer or copolymer block having a degree of polymerization of from 2 to 1,000, B is a short-chain connecting unit containing ester, amide, urea or urethane groups which groups are formed by (a) hydroxyl groups in A and carboxylic acid groups in B resulting in ester groups, (b) amino groups in A and carboxylic acid groups in B resulting in amide groups, (c) amino groups in A and isocyanate groups in B resulting in urea groups, (d) hydroxyl groups in A and isocyanate groups in B resulting in urethane groups and n is from 0 to 50.
Claim 3
Dependent Claim
51 words
The vinylpyrrolidone polymer of claim 1, wherein vinylpyrrolidone polymer blocks carrying hydroxyl groups as functional end groups are linked by aliphatic dicarboxylic acids having a chain of from 0 to 10 carbon atoms between the two carbonyl groups, said hydroxyl groups and said carbonyl groups forming ester groups as connecting units.
Claim 4
Dependent Claim
50 words
The vinylpyrrolidone polymer of claim 1, wherein vinylpyrrolidone polymer blocks carrying hydroxyl groups as functional end groups are linked by aliphatic diisocyanates having a chain of from 2 to 10 carbon atoms between the two isocyanate groups, said hydroxyl groups and said isocyanate groups forming urethane groups as connecting units.
Claim 5
Dependent Claim
25 words
The vinylpyrrolidone polymer of claim 2, wherein the vinylpyrrolidone polymer block carrying hydroxyl groups is a copolymer of vinylpyrrolidone with small amounts of a comonomer.
Claim 6
Dependent Claim
16 words
A vinylpyrrolidone polymer as set forth in claim 1 wherein A is a homopolymer of vinylpyrrolidone.
Claim 7
Dependent Claim
22 words
A vinylpyrrolidone polymer as set forth in claim 1 wherein the average molecular weight of the polymer is from 1,000 to 1,000,000.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-02 | 1984-09-01 | 1985-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-02 | 1988-09-01 | 1989-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-02 | 1992-09-01 | 1993-03-03 | $7700.00 | Window Closed / Lapsed |