US4254111A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sterolin products
Assignee: HOYER & Co KG GmbH
•
Filing: 1979-07-02
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Granted: 1981-03-03
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Expires: 1999-07-02
Abstract
Abstract The invention is concerned with new chemical compounds being the hemiesters of steryl glycosides, methods of preparing these hemiesters, and pharmaceutically, particularly anti-inflammatory, compositions containing the new hemiesters.
Inventors
- 👤 Karl H. Pegel
- 👤 Colin B. Rogers
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 12:25
CPC Classifications
C; C07; C07J; C07J17/00; C07J17/005; A; A61; A61P; A61P29/00
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
9 words
A pharmaceutically-acceptable dicarboxylic acid hemiester of a steryl glycoside.
Claim 2
Dependent Claim
9 words
A pharmaceutically-acceptable dicarboxylic acid hemiester of a steryl glycoside.
Claim 3
Dependent Claim
25 words
The compound according to claim 1 wherein the hemiester residue is derived from one of the group consisting of hemisuccinate, hemiglutarate, hemimaleate, hemicyclohexandicarboxylate and hemiphthalate.
Claim 4
Dependent Claim
33 words
The compound according to claim 1 or claim 2 consisting of the steryl glycoside from the group consisting of the glycosides of sitosterol, stigmasterol, ergosterol, cholesterol, 5a-cholestanol, lanosterol, 22,23-dihydrolanosterol, campasterol, cycloartenol and a-spinasterol.
Claim 5
Dependent Claim
22 words
An anti-inflammatory composition including a pharmaceutically-acceptable dicarboxylic acid hemiester of a steryl glycoside in a pharmaceutically-effective amount together with an inert carrier.
Claim 6
Dependent Claim
22 words
An anti-inflammatory composition including a pharmaceutically-acceptable dicarboxylic acid hemiester of a steryl glycoside in a pharmaceutically-effective amount together with an inert carrier.
Claim 7
Dependent Claim
37 words
An anti-inflammatory composition according to claim 4 wherein the hemiester is chosen from the group consisting of the hemisuccinates, hemiglutarates, hemimaleates, hemicyclohexandicarboxylates and hemiphthalates of sitosterol, stigmasterol, ergosterol, cholesterol, 5a-cholestanol, lanosterol, 22,23-dihydrolanosterol, campasterol, cycloartenol and a-spinasterol glycosides.
Claim 8
Dependent Claim
11 words
The composition of claim 5 wherein the glycoside is a glucoside.
Claim 9
Dependent Claim
11 words
The composition of claim 6 wherein the hemiester is a hemisuccinate.
Claim 10
Dependent Claim
11 words
The compound of claim 3 wherein the glycoside is a glucoside.
Claim 11
Dependent Claim
36 words
The compound of claim 1 wherein the hemiester is a hemisuccinate of a steryl glucoside wherein the sterol is chosen from the group consisting of sitosterol, stigmasterol, erogsterol, cholesterol, 5a-cholestenol, lanosterol, 22,23-dihydrolanosterol, campasterol, cycloartenol and a-spinasterol.
Claim 12
Dependent Claim
13 words
The compound of claim 9 wherein the glucoside is the glucoside of sitosterol.
Claim 13
Dependent Claim
39 words
The compound of claim 1 wherein the hemiester is a hemisuccinate of a steryl glycoside which is a glucoside, galactoside or maltoside of a sterol group consisting of sitosterol, stigmasterol, ergosterol, cholesterol, 5a-cholestanol, lanosterol, 22,23-dihydrolanosterol, campasterol, cycloartenol and a-spinasterol.
Claim 14
Dependent Claim
21 words
The method of treating an inflammatory illness comprising administering to a mammal an anti-inflammatory amount of a compound of claim 1.
Claim 15
Dependent Claim
46 words
The method of claim 12 wherein the hemiester is selected from the group consisting of hemissuccinates, hemiglutarates, hemimaleates, hemicyclohexandicarboxylates and hemiphthalates of a steryl glycoside wherein the sterol is chosen from the group consisting of sitosterol, stigmasterol, ergosterol, cholesterol, 5a-cholestanol, lanosterol, 22,23-dihydrolanosterol, campasterol, cycloartenol and a-spinasterol.
Claim 16
Dependent Claim
14 words
The method of claim 13 wherein the glycoside is a glucoside, galactoside or maltoside.
Claim 17
Dependent Claim
11 words
The method of claim 14 wherein the glycoside is a glucoside.
Claim 18
Dependent Claim
11 words
The method of claim 15 wherein the hemiester is a hemisuccinate.
Claim 19
Dependent Claim
11 words
The method of claim 14 wherein the hemiester is a hemisuccinate.
Claim 20
Dependent Claim
11 words
The method of claim 13 wherein the hemiester is a hemisuccinate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-02 | 1984-09-01 | 1985-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-02 | 1988-09-01 | 1989-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-02 | 1992-09-01 | 1993-03-03 | $7700.00 | Window Closed / Lapsed |