US4250303A
Expired / Lapsed
US
⏱️ 0.0 years remaining
N-Benzyl anthracyclines
Assignee: SRI International Inc
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Filing: 1979-08-24
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Granted: 1981-02-10
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Expires: 1999-08-24
Abstract
Abstract N-Benzyl and N,N-dibenzyl derivatives of the anthracycline compounds adriamycin and daunomycin, said derivatives having anticancer properties and being active against leukemia P-388 in mice, for example. The N,N-dibenzyl derivatives have the unique quality of exhibiting a loss of DNA-binding properties.
Inventors
- 👤 Helen Y. Wu
- 👤 Thomas H. Smith
- 👤 David W. Henry
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 06:18
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
13 words
The compound which is N,N-dibenzyl-13-dihydroadriamycin, together with its pharmaceutically acceptable acid addition salts.
Claim 2
Dependent Claim
13 words
The compound which is N,N-dibenzyl-13-dihydroadriamycin, together with its pharmaceutically acceptable acid addition salts.
References Cited (Backward Citations)
US3803124A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-10 | 1984-08-11 | 1985-02-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-10 | 1988-08-11 | 1989-02-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-10 | 1992-08-11 | 1993-02-10 | $7700.00 | Window Closed / Lapsed |