US4242504A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3"-Acylated macrolide antibiotics
Assignee: Asahi Kasei Corp
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Filing: 1979-05-10
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Granted: 1980-12-30
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Expires: 1999-05-10
Abstract
Abstract 3"-acylated macrolide antibiotics of the formula ##STR1## wherein R 1 is hydrogen or C 2-3 alkanoyl, R 2 is hydrogen or C 2-4 alkanoyl, at least one of R 1 and R 2 being hydrogen, and one of R' and R" being R 3 and the other R 4 , R 3 being C 2-6 alkanoyl and R 4 being C 2-5 alkanoyl, or a pharmaceutically acceptable salt thereof.
Inventors
- 👤 Hideo Sakakibara
- 👤 Osamu Okegawa
- 👤 Toshiyuki Watanabe
- 👤 Tatsuro Fujiwara
- 👤 Susumu Watanabe
- 👤 Satoshi Omura
- 👤 Tetsuo Matsuda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 11:08
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
71 words
A compound of the formula ##STR37## wherein R 1 is hydrogen or C 2-3 alkanoyl, R 2 is hydrogen or C 2-4 alkanoyl, at least one of R 1 and R 2 being hydrogen, and one of R' and R" is R 3 and the other is R 4 , in which R 3 is C 2-6 alkanoyl and R 4 is C 2-5 alkanoyl, or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
71 words
A compound of the formula ##STR37## wherein R 1 is hydrogen or C 2-3 alkanoyl, R 2 is hydrogen or C 2-4 alkanoyl, at least one of R 1 and R 2 being hydrogen, and one of R' and R" is R 3 and the other is R 4 , in which R 3 is C 2-6 alkanoyl and R 4 is C 2-5 alkanoyl, or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
58 words
A compound as claimed in claim 1, of the formula ##STR38## wherein R 1 is hydrogen or C 2-3 alkanoyl, R 2 is hydrogen or C 2-4 alkanoyl, at least one of R 1 and R 2 being hydrogen, R 3 is C 2-6 alkanoyl and R 4 is C 2-5 alkanoyl, or a pharmaceutically acceptable salt thereof.
Claim 4
Dependent Claim
35 words
A compound as claimed in claim 2, wherein R 1 is C 2-3 alkanoyl, R 2 is hydrogen, and R 3 and R 4 have the same meanings hereinabove, or a pharmaceutically acceptable salt thereof.
Claim 5
Dependent Claim
35 words
A compound as claimed in claim 3, wherein R 4 is propionyl, butylyl or isovaleryl, and R 1 , R 2 and R 3 have the same meanings hereinabove, or a pharmaceutically acceptable salt thereof.
Claim 6
Dependent Claim
39 words
A compound as claimed in claim 2, wherein R 1 is hydrogen and R 2 is C 2-4 alkanoyl, and R 3 and R 4 have the same meanings as in claim 2, or a pharmaceutically acceptable salt thereof.
Claim 7
Dependent Claim
37 words
A compound as claimed in claim 5, wherein R 4 is butylyl or isovaleryl, R 1 is C 2-3 alkanoyl, R 2 is hydrogen and R 3 is C 2-6 alkanoyl, or a pharmaceutically acceptable salt thereof.
Claim 8
Dependent Claim
35 words
A compound as claimed in claim 2, wherein R 1 or R 2 is hydrogen and R 3 and R 4 have the same meanings as in claim 2, or a pharmaceutically acceptable salt thereof.
Claim 9
Dependent Claim
37 words
A compound as claimed in claim 7, wherein R 4 is butylyl or isovaleryl, and R 1 , R 2 and R 3 have the same meanings as in claim 7, or a pharmaceutically acceptable salt thereof.
Claim 10
Dependent Claim
58 words
A compound as claimed in claim 1, of the formula ##STR39## wherein R 1 is hydrogen or C 2-3 alkanoyl, R 2 is hydrogen or C 2-4 alkanoyl, at least one of R 1 and R 2 being hydrogen, R 3 is C 2-6 alkanoyl, and R 4 is C 2-5 alkanoyl, or a pharmaceutically acceptable salt thereof.
Claim 11
Dependent Claim
25 words
A compound as claimed in claim 9, wherein R 1 is C 2-3 alkanoyl, and R 2 is hydrogen or a pharmaceutically acceptable salt thereof.
Claim 12
Dependent Claim
21 words
A compound as claimed in claim 10, wherein R 4 is propionyl, butylyl or isovaleryl, or a pharmaceutically acceptable salt thereof.
Claim 13
Dependent Claim
25 words
A compound as claimed in claim 9, wherein R 1 is hydrogen and R 2 is C 2-3 alkanoyl or a pharmaceutically acceptable salt thereof.
Claim 14
Dependent Claim
20 words
A compound as claimed in claim 12, wherein R 4 is butylyl or isovaleryl or a pharmaceutically acceptable salt thereof.
Claim 15
Dependent Claim
21 words
A compound as claimed in claim 9, wherein R 1 and R 2 are hydrogen or a pharmaceutically acceptable salt thereof.
Claim 16
Dependent Claim
20 words
A compound as claimed in claim 14, wherein R 4 is butylyl or isovaleryl or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-12-30 | 1984-06-30 | 1984-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-12-30 | 1988-06-30 | 1988-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-12-30 | 1992-06-30 | 1992-12-30 | $7700.00 | Window Closed / Lapsed |