US4242343A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Phenylpiperazine derivatives
Assignee: Synthelabo SA
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Filing: 1979-06-15
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Granted: 1980-12-30
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Expires: 1999-06-15
Abstract
Abstract Phenylpiperazine derivatives corresponding to the formula (I) ##STR1## in which n is 1, 2 or 3 and R represents the tetrahydrofuryl-2 radical, or the radical CH 2 -SH, or a radical CH 2 -S-alkyl, or a radical CH 2 -O-alkyl or a radical CH 2 -S-CO-alkyl, the alkyls having from 1 to 8 carbon atoms, and also their addition salts with pharmaceutically acceptable acids. These compounds are tranquilizers with psychotropic properties which permit their use in anxiety and depression.
Inventors
- 👤 Henry Najer
- 👤 Philippe Manoury
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:27
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/18; C07D207/22; C07D207/24; C07D207/26; C07D207/263; C07D207/27; C07D211/00; C07D211/04; C07D211/68; C07D211/72; C07D211/74; C07D211/76; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/62; C07D213/63; C07D213/64; C07D233/00; C07D233/04; C07D233/28; C07D233/30; C07D233/32; C07D233/36; C07D235/00; C07D235/02; C07D235/04; C07D235/24; C07D235/26; C07D263/00; C07D263/02; C07D263/08; C07D263/16; C07D263/18; C07D263/20; C07D263/22; C07D295/00; C07D295/04; C07D295/08; C07D295/084; C07D295/088; C07D307/00; C07D307/02; C07D307/04; C07D307/10; C07D307/14
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
63 words
Phenylpiperazine derivatives corresponding to the formula (I) ##STR11## in which n is 1,2 or 3 and R represents the tetrahydrofuryl-2 radical, or the radical CH 2 -SH, or a radical CH 2 -S-alkyl, or a radical CH 2 -O-alkyl or a radical CH 2 -S-CO-alkyl, the alkyls having from 1 to 8 carbon atoms, and also their addition salts with pharmaceutically acceptable acids.
Claim 2
Dependent Claim
63 words
Phenylpiperazine derivatives corresponding to the formula (I) ##STR11## in which n is 1,2 or 3 and R represents the tetrahydrofuryl-2 radical, or the radical CH 2 -SH, or a radical CH 2 -S-alkyl, or a radical CH 2 -O-alkyl or a radical CH 2 -S-CO-alkyl, the alkyls having from 1 to 8 carbon atoms, and also their addition salts with pharmaceutically acceptable acids.
Claim 3
Dependent Claim
30 words
Derivatives according to claim 1, in which n is equal to 1 and R is a radical CH 2 SH, CH 2 S-alkyl, CH 2 -O-alkyl or CH 2 SCO-alkyl.
Claim 4
Dependent Claim
13 words
Derivatives according to claim 2, in which the alkyl is the methyl radical.
Claim 5
Dependent Claim
10 words
A compound according to claim 1, which is 1-(m-trifluoromethylthio-phenyl)-4-(2-tetrahydrofurylmethyl) piperazine.
Claim 6
Dependent Claim
17 words
A pharmaceutical composition which contains a compound as specified in claim 1 in an effective tranquilizing dosage.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-12-30 | 1984-06-30 | 1984-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-12-30 | 1988-06-30 | 1988-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-12-30 | 1992-06-30 | 1992-12-30 | $7700.00 | Window Closed / Lapsed |