Abstract A method for preparing human and other animal unbilical cords for use as a vascular replacement and/or arterial venous fistula which permits the umbilical cord which is to be grafted to be preformed into a desired predetermined configuration. The method includes the steps of initially flushing the cord in an aqueous solution, and then mounting the flushed cord upon a mandrel having the desired configuration. The mounted cord is immersed in ethyl alcohol until substantially dehydrated and preformed, and is thereafter immersed for fixation in an aldehyde selected from the class consisting of dialdehyde starch and gluteraldehyde, with the aldehyde immersion fixing the tissue into a shape conforming to the mandrel upon which it is mounted.
The method of conforming a human umbilical cord to a predetermined configuration for implanting in a human body which method comprises the steps of: (a) flushing the cord and thereafter mounting the cord upon a mandrel of the desired configuration; (b) initially immersing the mounted cord and manlvml into an aqueous solution of ethyl alcohol containing more than about 70% of ethyl alcohol until said cord is substantially dehydrated and shrunk onto said mandrel; and (c) thereafter immersing the dehydrated and mounted cord in an aqueous solution selected from the group consisting of dialdehyde starch in water and gluteraldehyde in water, wherein said solution contains more than about 1% of said aldehyde, for a period sufficiently long to permit the configuration to become fixed.
Claim 2
Independent Claim
124 words
The method of conforming a human umbilical cord to a predetermined configuration for implanting in a human body which method comprises the steps of: (a) flushing the cord and thereafter mounting the cord upon a mandrel of the desired configuration; (b) initially immersing the mounted cord and manlvml into an aqueous solution of ethyl alcohol containing more than about 70% of ethyl alcohol until said cord is substantially dehydrated and shrunk onto said mandrel; and (c) thereafter immersing the dehydrated and mounted cord in an aqueous solution selected from the group consisting of dialdehyde starch in water and gluteraldehyde in water, wherein said solution contains more than about 1% of said aldehyde, for a period sufficiently long to permit the configuration to become fixed.
Claim 3
Dependent Claim
28 words
The method as defined in claim 1 being particularly characterized in that immersion in said ethyl alcohol solution extends for a period of at least about 18 hours.
Claim 4
Dependent Claim
22 words
The method as defined in claim 1 being particularly characterized in that said aldehyde solution contains approximately 1.3% of aldehyde in water.