US4239754A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Liposomes containing heparin and a process for obtaining them
Assignee: Choay SA
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Filing: 1977-10-25
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Granted: 1980-12-16
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Expires: 1997-10-25
Abstract
Abstract Heparin-based preparations wherein heparin is retained in or on liposomes. The lipids of said liposomes are preferably phospholipids comprising acyl chains derived from non saturated fatty acids, advantageously essential acids. These heparin-liposomes preparations have heparinic activity when administered in vivo by the oral route and a delayed-type action.
Inventors
- 👤 Edgar Sache
- 👤 Henri Bertrand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:26
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K9/00; A61K9/10; A61K9/127; A61P; A61P7/00; A61P7/02
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
53 words
A method for the control of blood coagulability in vivo comprising orally adminstering in an amount effective to control blood coagulation a pharmaceutical composition comprising orally administrable heparin-liposomes, the lipids of which are formed of non-toxic physiologically acceptable and metabolizable phospholipids, with heparin retained therein or thereon in association with a pharmaceutical vehicle.
Claim 2
Independent Claim
53 words
A method for the control of blood coagulability in vivo comprising orally adminstering in an amount effective to control blood coagulation a pharmaceutical composition comprising orally administrable heparin-liposomes, the lipids of which are formed of non-toxic physiologically acceptable and metabolizable phospholipids, with heparin retained therein or thereon in association with a pharmaceutical vehicle.
Claim 3
Independent Claim
46 words
A method for the control of blood coagulability in vivo comprising orally administering in an amount effective to control blood coagulation a pharmaceutical composition comprising orally administrable heparin-liposomes, the lipids of which comprise lecithin, with heparin retained therein or thereon in association with a pharmaceutical vehicle.
Claim 4
Independent Claim
46 words
A method for the control of blood coagulability in vivo comprising orally administering in an amount effective to control blood coagulation a pharmaceutical composition comprising orally administrable heparin-liposomes, the lipids of which comprise lecithin, with heparin retained therein or thereon in association with a pharmaceutical vehicle.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-12-16 | 1984-06-16 | 1984-12-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-12-16 | 1988-06-16 | 1988-12-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-12-16 | 1992-06-16 | 1992-12-16 | $7700.00 | Window Closed / Lapsed |