US4236633A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for storage
Assignee: Astra Lakemedel AB
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Filing: 1978-08-25
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Granted: 1980-12-02
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Expires: 1998-08-25
Abstract
Abstract The present invention relates to a process for preventing decomposition by oxidation of substances sensitive to oxidation, which substances are present in pharmaceutically active preparations in the form of solutions. The preparations present in ampoules, disposable syringes, vials and the like are thereby enclosed in an outer package made of oxygen impervious material, into which outer package hydrogen and a catalyst, capable of catalyzing the reaction of hydrogen and oxygen to water, is introduced, and such a package.
Inventors
- 👤 Lennart S. Ernerot
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 19:49
CPC Classifications
B; B65; B65D; B65D81/00; B65D81/24; A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; B65B; B65B31/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
76 words
Package for the protection of oxidizable compounds selected from the group consisting of adrenaline, noradrenaline and derivatives thereof which are present in pharmaceutically active solutions containing a local anesthetically active compound, which solutions are stored in a container which is further enclosed in an oxygen gas impervious outer package containing hydrogen gas and a catalyst which catalyzes the reaction of hydrogen and oxygen into water present in the space between said container and said outer package.
Claim 2
Dependent Claim
76 words
Package for the protection of oxidizable compounds selected from the group consisting of adrenaline, noradrenaline and derivatives thereof which are present in pharmaceutically active solutions containing a local anesthetically active compound, which solutions are stored in a container which is further enclosed in an oxygen gas impervious outer package containing hydrogen gas and a catalyst which catalyzes the reaction of hydrogen and oxygen into water present in the space between said container and said outer package.
Claim 3
Dependent Claim
22 words
Package according to claim 1, characterized in that the volume of hydrogen gas is at least twice the volume of oxygen gas.
Claim 4
Dependent Claim
19 words
Package according to any of claims 1 or 2, characterized in that the outer package further comprises inert gas.
Claim 5
Dependent Claim
16 words
Package according to claim 1, characterized in that the outer package consists of a metal container.
Claim 6
Dependent Claim
38 words
Package according to claim 4, characterized in that the outer package consists of a laminate composed of aluminum foil-plastic foil, which laminate has been sealed via the plastic foil to the formation of a space receiving said units.
Claim 7
Independent Claim
82 words
A method for preventing oxidation of a compound selected from the group consisting of adrenaline, noradrenaline, and derivatives thereof which are sensitive to oxidation and present in pharmaceutically active solutions containing a local anesthetically active compound and stored in a container wherein said container is further enclosed in an oxygen gas impervious outer package and hydrogen gas and a catalyst which catalyzes the reaction of hydrogen and oxygen to water are introduced into the space between said container and said outer package.
Claim 8
Independent Claim
82 words
A method for preventing oxidation of a compound selected from the group consisting of adrenaline, noradrenaline, and derivatives thereof which are sensitive to oxidation and present in pharmaceutically active solutions containing a local anesthetically active compound and stored in a container wherein said container is further enclosed in an oxygen gas impervious outer package and hydrogen gas and a catalyst which catalyzes the reaction of hydrogen and oxygen to water are introduced into the space between said container and said outer package.
Claim 9
Dependent Claim
29 words
Process according to claim 6, characterized in that the volume of the hydrogen gas introduced is at least twice the volume of oxygen gas present in the outer package.
Claim 10
Dependent Claim
22 words
Process according to claim 6, characterized in that one introduces inert gas into the package prior to the introduction of hydrogen gas.
Claim 11
Dependent Claim
19 words
Process according to claim 6, characterized in that one evacuates the package prior to the introduction of hydrogen gas.
Claim 12
Dependent Claim
28 words
Process according to claims 6 or 4, characterized in that one carries out an introduction of inert gas prior to the evacuation and the introduction of hydrogen gas.
Claim 13
Dependent Claim
28 words
Process according to claim 6, characterized in that one introduces hydrogen gas in an amount that is up to 8% of the inner free volume of the package.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-12-02 | 1984-06-02 | 1984-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-12-02 | 1988-06-02 | 1988-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-12-02 | 1992-06-02 | 1992-12-02 | $7700.00 | Window Closed / Lapsed |