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US4235967A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for producing antibiotics by cultivation of Streptomyces flavogriseus

Assignee: Merck and Co Inc
•
Filing: 1979-04-06
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Granted: 1980-11-25
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Expires: 1999-04-06
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Abstract

Abstract The antibiotics MSD 890A1 and MSD 890A3 and pharmaceutically acceptable salts thereof (hereinafter referred to as antibiotics 890A1 and 890A3) are active against both gram-positive and gram-negative bacteria. The antibiotics are produced by growing species of Streptomyces on suitable fermentation media.

Inventors

  • 👤 Patrick J. Cassidy
  • 👤 Robert T. Goegelman
  • 👤 Edward O. Stapley
  • 👤 Sebastian Hernandez

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 20:07
CPC Classifications
C; C12; C12P; C12P17/00; C12P17/18; C12P17/182; C12P17/184; C12N; C12N1/00; C12N1/20; C12N1/205; C12R; C12R2001/00; C12R2001/01; C12R2001/465; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/886

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 52 words
A process for the production of antibiotic 890A 1 which comprises cultivating a strain of Streptomyces flavogriseus selected from the group consisting of Streptomyces flavogriseus NRRL 8139 and NRRL 8140 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotic.
Claim 2
Dependent Claim 52 words
A process for the production of antibiotic 890A 1 which comprises cultivating a strain of Streptomyces flavogriseus selected from the group consisting of Streptomyces flavogriseus NRRL 8139 and NRRL 8140 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotic.
Claim 3
Dependent Claim 38 words
A process for the production of antibiotic 890A 3 which comprises cultivating Streptomyces flavogriseus NRRL 8139 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotic.
Claim 4
Dependent Claim 38 words
A process for the production of antibiotic 890A 3 which comprises cultivating Streptomyces flavogriseus NRRL 8139 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotic.
Claim 5
Dependent Claim 45 words
A process for the production of the mixture comprising antibiotic 890A 1 and antibiotic 890A 3 which comprises cultivating Streptomyces flavogriseus NRRL 8139 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotics.
Claim 6
Dependent Claim 45 words
A process for the production of the mixture comprising antibiotic 890A 1 and antibiotic 890A 3 which comprises cultivating Streptomyces flavogriseus NRRL 8139 in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering said antibiotics.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-11-25 1984-05-26 1984-11-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-11-25 1988-05-26 1988-11-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-11-25 1992-05-26 1992-11-25 $7700.00 Window Closed / Lapsed

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