US4234645A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical composition
Assignee: Procter and Gamble Co
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Filing: 1978-08-04
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Granted: 1980-11-18
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Expires: 1998-08-04
Abstract
Abstract Dichloromethane diphosphonates affect the biosynthesis of collagen.
Inventors
- 👤 Harald Gunther
- 👤 Herbert C. Fleisch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 19:48
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A23; A23K; A23K20/00; A23K20/10; A23K20/105; A61P; A61P29/00; A61P37/00; A61P37/02; A61P37/06
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
58 words
A method for treating ankylosing spondylitis in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 2
Independent Claim
58 words
A method for treating ankylosing spondylitis in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 3
Independent Claim
58 words
A method for treating rheumatic fever in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 4
Independent Claim
58 words
A method for treating rheumatic fever in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 5
Independent Claim
58 words
A method for treating systemic lupus in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 6
Independent Claim
58 words
A method for treating systemic lupus in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 7
Independent Claim
58 words
A method for treating wound healing in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 8
Independent Claim
58 words
A method for treating wound healing in humans and lower animals comprising administering to a human or lower animal in need of such treatment a safe and effective amount of a pharmaceutically-acceptable dichloromethane diphosphonate compound selected from the group consisting of dichloromethane diphosphonic acid, salts of dichloromethane diphosphonic acid, and alkyl and aryl esters of dichloromethane diphosphonic acid.
Claim 9
Dependent Claim
21 words
A method according to claim 4 wherein the dichloromethane diphosphonate compound is applied topically to the afflicted situs of the wound.
Claim 10
Independent Claim
23 words
A method according to claims 1, 2, 3, or 4 wherein the dichloromethane diphosphonate compound comprises the sodium salt form of dichloromethane diphosphonate.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-18 | 1984-05-19 | 1984-11-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-18 | 1988-05-19 | 1988-11-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-18 | 1992-05-19 | 1992-11-18 | $7700.00 | Window Closed / Lapsed |