US4233313A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Analgesic potentiation
Assignee: Janssen Pharmaceuticals Inc
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Filing: 1978-12-18
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Granted: 1980-11-11
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Expires: 1998-12-18
Abstract
Abstract A method of producing analgesia by orally administering 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid or salt thereof.
Inventors
- 👤 Joseph F. Gardocki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 20:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61K31/403; A61K31/404; A61K31/405
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
61 words
A method for producing analgesia which comprises orally administering to a subject suffering from pain (1) from about 0.13 to 0.27 mg/kg of body weight of a 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid compound, said compound being selected from 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid having the formula ##STR2## and (b) and therapeutically acceptable salts thereof, and (2) from about 3.8 to 7.5 mg/kg of body weight of acetaminophen.
Claim 2
Independent Claim
61 words
A method for producing analgesia which comprises orally administering to a subject suffering from pain (1) from about 0.13 to 0.27 mg/kg of body weight of a 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid compound, said compound being selected from 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid having the formula ##STR2## and (b) and therapeutically acceptable salts thereof, and (2) from about 3.8 to 7.5 mg/kg of body weight of acetaminophen.
Claim 3
Independent Claim
49 words
A method for producing analgesia which comprises orally administering to a subject suffering from pain (1) as primary antinociceptive agent, from about 8 to 16 milligrams of 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid or a non-toxic therapeutically acceptable salt thereof, and (2) as potentiating agent, from about 225 to 450 milligrams of acetaminophen.
Claim 4
Independent Claim
49 words
A method for producing analgesia which comprises orally administering to a subject suffering from pain (1) as primary antinociceptive agent, from about 8 to 16 milligrams of 1-(p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetic acid or a non-toxic therapeutically acceptable salt thereof, and (2) as potentiating agent, from about 225 to 450 milligrams of acetaminophen.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-11 | 1984-05-12 | 1984-11-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-11 | 1988-05-12 | 1988-11-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-11 | 1992-05-12 | 1992-11-11 | $7700.00 | Window Closed / Lapsed |