US4233231A
Expired / Lapsed
US
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Novel vinyl-stannyl derivatives
Assignee: Wyeth Holdings LLC
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Filing: 1977-11-22
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Granted: 1980-11-11
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Expires: 1997-11-22
Abstract
Abstract Vinylstannyl derivatives and the processes for their conversion to vinyliodides, vinylbromides and vinyllithium reagents. The vinylstannyl, vinyliodides, vinylbromide derivatives and vinyllithiums are useful as intermediates for the preparation of prostaglandin analogs.
Inventors
- 👤 Middleton B. Floyd, Jr.
- 👤 Charles V. Grudzinskas
- 👤 Sow-mei L. Chen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 13:45
CPC Classifications
C; C07; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/0803; C07C; C07C29/00; C07C29/09; C07C29/095; C07C29/10; C07C29/36; C07C29/38; C07C29/42; C07C405/00; C07F7/18; C07F7/1804; C07F7/22; C07F7/2208; C07B; C07B2200/00; C07B2200/07; C07B2200/09; C07C2601/00; C07C2601/06; C07C2601/08; C07C2601/12; C07C2601/14
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
133 words
A compound of the formula: ##STR8## wherein R 1 is selected from the group consisting of C 1 -C 5 alkyl; R is selected from the group consisting of ##STR9## wherein R 5 is selected from the group consisting of C 4 -C 7 alkyl, R 6 is selected from the group consisting of C 5 -C 6 alkyl R 7 is selected from the group consisting of C 2 -C 5 alkyl, R 8 is methyl or ethyl, R 10 is selected from the group consisting of C 1 -C 4 alkyl, R 11 is selected from the group consisting of C 3 -C 6 alkyl, benzyl, 2-butyne and 2-butene, n is the integer 1 or 2, p is the integer 1 or 2, and q is the integer 1 or 2.
Claim 2
Dependent Claim
133 words
A compound of the formula: ##STR8## wherein R 1 is selected from the group consisting of C 1 -C 5 alkyl; R is selected from the group consisting of ##STR9## wherein R 5 is selected from the group consisting of C 4 -C 7 alkyl, R 6 is selected from the group consisting of C 5 -C 6 alkyl R 7 is selected from the group consisting of C 2 -C 5 alkyl, R 8 is methyl or ethyl, R 10 is selected from the group consisting of C 1 -C 4 alkyl, R 11 is selected from the group consisting of C 3 -C 6 alkyl, benzyl, 2-butyne and 2-butene, n is the integer 1 or 2, p is the integer 1 or 2, and q is the integer 1 or 2.
Claim 3
Dependent Claim
26 words
A compound according to claim 1, wherein R is as previously defined; and R 1 is butyl (CH 3 CH 2 CH 2 CH 2 --).
Claim 4
Dependent Claim
7 words
The compound according to claim 2, (E)-1-tri-n-butylstannyl-3-triethylsilyloxy-1-octene.
Claim 5
Dependent Claim
71 words
A compound of the formula ##STR10## wherein R 1 is selected from the group cinsisting of C 1 to C 5 alkyl; R is selected from the group consisting of ##STR11## wherein R 6 ' is selected from the group consisting of C 3 to C 6 alkyl, R 6 " is selected from the group consisting of C 4 to C 6 alkyl and R 8 is methyl or ethyl.
Claim 6
Dependent Claim
71 words
A compound of the formula ##STR10## wherein R 1 is selected from the group cinsisting of C 1 to C 5 alkyl; R is selected from the group consisting of ##STR11## wherein R 6 ' is selected from the group consisting of C 3 to C 6 alkyl, R 6 " is selected from the group consisting of C 4 to C 6 alkyl and R 8 is methyl or ethyl.
Claim 7
Dependent Claim
25 words
The compound of claim 4 wherein R is as previously defined and R 1 is butyl (CH 3 CH 2 CH 2 CH 2 ).
Claim 8
Dependent Claim
7 words
The compound according to claim 5, (E)-4-triethylsilyloxy-1-tri-n-butylstannyl-1-octene.
Claim 9
Dependent Claim
7 words
The compound according to claim 2, (E)-4-triethylsilyloxy-1-tri-n-butylstannyl-1,5-trans-nonadiene.
Claim 10
Dependent Claim
7 words
The compound according to claim 2, (E)-4-triethylsilyloxy-5-methyl-1-tri-n-butylstannyl-1-octene.
Claim 11
Dependent Claim
7 words
The compound according to claim 2, (E)-4-trimethylsilyloxy-4-methyl-1-tri-n-butylstannyl-1,5-trans-octadiene.
Claim 12
Dependent Claim
7 words
The compound according to claim 5, (E)-4(R)-triethylsilyloxy-1-tri-n-butylstannyl-1-octene.
Claim 13
Dependent Claim
7 words
The compound according to claim 5, (E)-4(S)-triethylsilyloxy-1-tri-n-butylstannyl-1-octene.
Claim 14
Dependent Claim
7 words
The compound according to claim 5, 1-(E-3-tri-n-butylstannyl-2-propenyl)-1-trimethylsilyloxy-cyclohexane.
Claim 15
Dependent Claim
7 words
The compound according to claim 5, 1-(E-3-tri-n-butylstannyl-2-propenyl)-1-trimethylsilyloxy-cyclopentane.
Claim 16
Dependent Claim
7 words
The compound according to claim 2, (E)-1-tri-n-butylstannyl-3-methyl-3-trimethylsilyloxy-1-octene.
Claim 17
Dependent Claim
7 words
The compound according to claim 5, (E)-1-tri-n-butylstannyl-4,4-dimethyl-3-trimethylsilyloxy-1-octene.
Claim 18
Dependent Claim
7 words
The compound according to claim 2, (E)-1-tri-n-butylstannyl-4,4-trimethylene-3-trimethylsilyloxy-1-octene.
Claim 19
Dependent Claim
7 words
The compound according to claim 2, (E)-1-tri-n-butylstannyl-4,4-trimethylene-3-trimethylsilyloxy-5-phenyl-1-pentene.
Claim 20
Dependent Claim
7 words
A compound according to claim 2, (E)-1-tri-n-butylstannyl-4,4-trimethylene-3-trimethylsilyloxy-6-yn-1-octene.
Claim 21
Dependent Claim
7 words
The compound according to claim 2, (E)-1-tri-n-butylstannyl-4,4-trimethylene-3-trimethylsilyloxy-6-cis-1-octadiene.
Claim 22
Dependent Claim
7 words
The compound according to claim 2, 1-[(E)-2-tri-n-butylstannylethylene]-1-trimethylsilyloxy-cyclohexane.
Claim 23
Dependent Claim
7 words
The compound according to claim 2, 1-[(E)-2-tri-n-butylstannylethylene]-1-trimethylsilyloxy-cyclopentane.
References Cited (Backward Citations)
US4038308A
Cited
US4087447A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-11 | 1984-05-12 | 1984-11-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-11 | 1988-05-12 | 1988-11-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-11 | 1992-05-12 | 1992-11-11 | $7700.00 | Window Closed / Lapsed |