US4231930A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1-Substituted thiomethyltriazolobenzodiazepines
Assignee: Shionogi and Co Ltd
•
Filing: 1979-03-01
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Granted: 1980-11-04
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Expires: 1999-03-01
Abstract
Abstract A compound of the formula: <IMAGE> wherein R is hydrogen, 2-5C alkoxycarbonyl, 1-7C acyl, 1-4C alkylthio, 7-10C phenylalkylthio, phenylthio, halo-phenylthio, disubstituted aminothio, <IMAGE> +TR <IMAGE> R1 is hydrogen or halogen; R2 is halogen or nitro; and its pharmaceutically acceptable acid addition salts. The compounds and salts thereof are useful as psychotropic agents and as anxiolytics, anticonvulsants and hypnotics.
Inventors
- 👤 Kentaro Hirai
- 👤 Toshio Fujishita
- 👤 Teruyuki Ishiba
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 04:59
CPC Classifications
C; C07; C07D; C07D249/00; C07D249/02; C07D249/08; A; A61; A61P; A61P21/00; A61P21/02; A61P25/00; A61P25/08; A61P25/20; C07D487/00; C07D487/02; C07D487/04; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
35 words
A compound of the formula: ##STR17## wherein R is 1-4C alkylthio, 7-10C phenylakylthio, phenylthio and halo-phenylthio; R 1 is hydrogen or halogen; R 2 is halogen or nitro; and its pharmaceutically acceptable acid addition salt.
Claim 2
Dependent Claim
35 words
A compound of the formula: ##STR17## wherein R is 1-4C alkylthio, 7-10C phenylakylthio, phenylthio and halo-phenylthio; R 1 is hydrogen or halogen; R 2 is halogen or nitro; and its pharmaceutically acceptable acid addition salt.
Claim 3
Dependent Claim
8 words
A compound according to claim 1, namely 8-chloro-1-(benzyldithio)methyl-6-(2-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Claim 4
Dependent Claim
8 words
A compound according to claim 1, namely 8-chloro-1-(4-chlorophenyldithio)methyl-6-(2-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Claim 5
Dependent Claim
8 words
A compound according to claim 1, namely 8-chloro-1-(t-butyldithio)methyl-6-(2-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
References Cited (Backward Citations)
US3886174A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-04 | 1984-05-05 | 1984-11-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-04 | 1988-05-05 | 1988-11-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-04 | 1992-05-05 | 1992-11-04 | $7700.00 | Window Closed / Lapsed |