US4230705A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety
Assignee: Wyeth Holdings LLC
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Filing: 1976-09-22
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Granted: 1980-10-28
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Expires: 1996-09-22
Abstract
Abstract This disclosure describes novel substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines useful as anxiolytic agents.
Inventors
- 👤 George R. Allen, Jr.
- 👤 John W. Hanifin, Jr.
- 👤 Daniel B. Moran
- 👤 Jay D. Albright
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 20:14
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/14; C07D295/145; C07D237/00; C07D237/02; C07D237/04; C07D237/06; C07D237/08; C07D237/10; C07D237/12; C07D237/14; C07D237/20; C07D487/00; C07D487/02; C07D487/04
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
110 words
The method of meliorating anxiety in a mammal which comprises administering internally to said mammal an effective amount of a compound selected from the group consisting of those of the formula: ##STR3## wherein R 1 , R 2 , and R 3 are each individually selected from the group consisting of hydrogen and alkyl having up to four carbon atoms with the first proviso that when R 1 and R 2 are both hydrogen then R 3 may not be methyl and with the second proviso that when R 2 and R 3 are both methyl then R 1 may not be hydrogen; and the pharmacologically acceptable acid-addition salts thereof.
Claim 2
Independent Claim
110 words
The method of meliorating anxiety in a mammal which comprises administering internally to said mammal an effective amount of a compound selected from the group consisting of those of the formula: ##STR3## wherein R 1 , R 2 , and R 3 are each individually selected from the group consisting of hydrogen and alkyl having up to four carbon atoms with the first proviso that when R 1 and R 2 are both hydrogen then R 3 may not be methyl and with the second proviso that when R 2 and R 3 are both methyl then R 1 may not be hydrogen; and the pharmacologically acceptable acid-addition salts thereof.
Claim 3
Dependent Claim
130 words
A therapeutic composition in dosage unit form useful for meliorating anxiety in mammals comprising from about 0.03 milligram to about 10.0 milligrams per kilogram of body weight per daily dosage unit, in association with a pharmaceutical carrier, of a compound selected from the group consisting of those of the formula: ##STR4## wherein R 1 , R 2 , and R 3 l are each individually selected from the group consisting of hydrogen and alkyl having up to four carbon atoms with the first proviso that when R 1 and R 2 are both hydrogen then R 3 may not be methyl and with the second proviso that when R 2 and R 3 are both methyl then R 1 may not be hydrogen; and the pharmacologically acceptable acid-addition salts thereof.
Claim 4
Dependent Claim
130 words
A therapeutic composition in dosage unit form useful for meliorating anxiety in mammals comprising from about 0.03 milligram to about 10.0 milligrams per kilogram of body weight per daily dosage unit, in association with a pharmaceutical carrier, of a compound selected from the group consisting of those of the formula: ##STR4## wherein R 1 , R 2 , and R 3 l are each individually selected from the group consisting of hydrogen and alkyl having up to four carbon atoms with the first proviso that when R 1 and R 2 are both hydrogen then R 3 may not be methyl and with the second proviso that when R 2 and R 3 are both methyl then R 1 may not be hydrogen; and the pharmacologically acceptable acid-addition salts thereof.
References Cited (Backward Citations)
GB1187281A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-28 | 1984-04-28 | 1984-10-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-28 | 1988-04-28 | 1988-10-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-28 | 1992-04-28 | 1992-10-28 | $7700.00 | Window Closed / Lapsed |