US4229467A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Alkoxy benzofuran carboxylic acids and salts and esters thereof as hypolipidemic agents
Assignee: Richardson Vicks Inc
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Filing: 1979-08-16
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Granted: 1980-10-21
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Expires: 1999-08-16
Abstract
Abstract Compounds of the Formula ##STR1## wherein R is H or C 1-4 alkyl; R 1 is H or C 1-4 alkyl; and R 2 is straight or branched chain alkyl of 10-20 carbon atoms, straight or branched chain alkenyl of 10-20 carbon atoms, straight or branched chain alkadienyl of 10-20 carbon atoms or straight or branched chain alkatrienyl of 10-20 carbon atoms and the pharmaceutically acceptable salts thereof, are useful as hypolipidemic agents.
Inventors
- 👤 Roger A. Parker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 02:59
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/82; C07D307/84; C07D307/85; A; A61; A61P; A61P3/00; A61P3/06; C07D307/86
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
69 words
A compound of the formula ##STR6## wherein R is H or C 1-4 alkyl; R 1 is H or C 1-4 alkyl; and R 2 is straight or branched chain alkyl of 10-20 carbon atoms, straight or branched chain alkenyl of 10-20 carbon atoms, straight or branched chain alkadienyl of 10-20 carbon atoms or straight or branched chain alkatrienyl of 10-20 carbon atoms, and the pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
69 words
A compound of the formula ##STR6## wherein R is H or C 1-4 alkyl; R 1 is H or C 1-4 alkyl; and R 2 is straight or branched chain alkyl of 10-20 carbon atoms, straight or branched chain alkenyl of 10-20 carbon atoms, straight or branched chain alkadienyl of 10-20 carbon atoms or straight or branched chain alkatrienyl of 10-20 carbon atoms, and the pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
13 words
A compound of claim 1, wherein R 2 is of 12-16 carbon atoms.
Claim 4
Dependent Claim
10 words
A compound of claim 2, wherein R 2 is tetradecyl.
Claim 5
Dependent Claim
10 words
A compound of claim 1, wherein R 1 is H.
Claim 6
Dependent Claim
11 words
A compound of claim 1, wherein R is H or methyl.
Claim 7
Dependent Claim
13 words
A compound of claim 1, wherein R 2 O is at the 6-position.
Claim 8
Dependent Claim
7 words
6-Tetradecyloxy-benzofuran-2-carboxylic acid, a compound of claim 1.
Claim 9
Dependent Claim
7 words
6-Tetradecyloxy-3-methyl-benzofuran-2-carboxylic acid, a compound of claim 1.
Claim 10
Dependent Claim
30 words
A pharmaceutical composition comprising in unit dosage form from about 50 mg to 1 g of a compound of claim 1 and a significant amount of a pharmaceutically acceptable carrier.
Claim 11
Dependent Claim
29 words
A method of lowering serum lipids in a mammal which comprises administering thereto an amount of a compound of claim 1 effective to lower significantly the serum lipids thereof.
References Cited (Backward Citations)
GB1008260A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-21 | 1984-04-21 | 1984-10-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-21 | 1988-04-21 | 1988-10-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-21 | 1992-04-21 | 1992-10-21 | $7700.00 | Window Closed / Lapsed |