US4225581A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biological materials
Assignee: Individual
•
Filing: 1978-08-07
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Granted: 1980-09-30
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Expires: 1998-08-07
Abstract
Abstract There are described processes for the preparation of submicroscopic particles of physiologically acceptable polymer associated with a biologically active material, by polymerizing a monomer in the presence of the biologically active material or by adsorbing the biologically active material upon preformed submicroscopic polymer particles. Where the biologically active material is an antigen, the particles are useful as constituents of injectable vaccines having an adjuvant effect.
Inventors
- 👤 Jorg Kreuter
- 👤 Peter P. Speiser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 21:46
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/385; A61K41/00; A61K41/10; A61K41/17; C; C12; C12N; C12N11/00; C12N11/02; C12N11/04; C12N11/08; C12N11/082; C12N11/087; C12N11/098; A61K2039/60; A61K2039/6093; A61K2039/62; A61K2039/622; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/788; Y10S977/795; Y10S977/84; Y10S977/895; Y10S977/896; Y10S977/897; Y10S977/898; Y10S977/902; Y10S977/904; Y10S977/915; Y10S977/917; Y10S977/918
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
58 words
Submicroscopic particles of a polymerized styrene or acrylic monomer on which is absorbed an antigen, in suspension or colloidical solution in a sterile aqueous medium, wherein the submicroscopic particles have a particle size of from 50 to 500 nm diameters, whereby the submicroscopic particles are formed by suspending the polymeric particles in a liquid medium containing the antigen.
Claim 2
Dependent Claim
58 words
Submicroscopic particles of a polymerized styrene or acrylic monomer on which is absorbed an antigen, in suspension or colloidical solution in a sterile aqueous medium, wherein the submicroscopic particles have a particle size of from 50 to 500 nm diameters, whereby the submicroscopic particles are formed by suspending the polymeric particles in a liquid medium containing the antigen.
Claim 3
Dependent Claim
17 words
A method of preventing infectious disease in mammals by injection of a vaccine according to claim 1.
References Cited (Backward Citations)
US4021364A
Cited
US4107288A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-30 | 1984-03-31 | 1984-09-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-30 | 1988-03-31 | 1988-09-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-30 | 1992-03-31 | 1992-09-30 | $7700.00 | Window Closed / Lapsed |