US4225495A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines
Assignee: ER Squibb and Sons LLC
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Filing: 1978-12-07
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Granted: 1980-09-30
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Expires: 1998-12-07
Abstract
Abstract Compounds having the formula ##STR1## wherein R is hydrogen or alkyl, n is 0 or 1 and m is 1 or 2 have hypotensive activity. Those compounds of the above formula wherein n is 1 are useful intermediates for the preparation of other hypotensive agents having the formula ##STR2##
Inventors
- 👤 Miguel A. Ondetti
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 19:54
CPC Classifications
C; C07; C07D; C07D513/00; C07D513/02; C07D513/04; A; A61; A61P; A61P9/00; A61P9/12; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
29 words
A compound having the formula ##STR12## wherein R is hydrogen or alkyl of 1 to 7 carbon atoms; m is 1 or 2; and n is 0 or 1.
Claim 2
Dependent Claim
29 words
A compound having the formula ##STR12## wherein R is hydrogen or alkyl of 1 to 7 carbon atoms; m is 1 or 2; and n is 0 or 1.
Claim 3
Dependent Claim
15 words
A compound in accordance with claim 1 wherein m is 1 and n is 1.
Claim 4
Dependent Claim
11 words
A compound in accordance with claim 1 wherein R is hydrogen.
Claim 5
Dependent Claim
17 words
A compound in accordance with claim 1 wherein R is alkyl of 1 to 7 carbon atoms.
Claim 6
Dependent Claim
11 words
A compound in accordance with claim 4 wherein R is methyl.
Claim 7
Dependent Claim
8 words
The compound in accordance with claim 1, (4S,9aS)-hexahydro-4-methyl-1H,5H-pyrrolo-[2,1-c][1,4]-thiazepine-1,5-dione.
References Cited (Backward Citations)
US2891000A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-30 | 1984-03-31 | 1984-09-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-30 | 1988-03-31 | 1988-09-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-30 | 1992-03-31 | 1992-09-30 | $7700.00 | Window Closed / Lapsed |