US4224339A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of disturbed keratinization
Assignee: Individual
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Filing: 1978-10-10
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Granted: 1980-09-23
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Expires: 1998-10-10
Abstract
Abstract Preventive as well as therapeutic treatment to alleviate the symptoms of disturbed keratinization, consisting of the topical application of a solution, gel, lotion, cream, ointment, stick, powder or spray containing one or more cysteic acid compounds, is disclosed. The compounds include free acid, ammonium salt, amine salt, metal chelate and metallic salt forms of cysteic acid, cysteine sulfinic acid and homocysteic acid. The efficacious compositions may include the active ingredients present in a total amount of from 0.1 to 30 percent by weight. Topical application to affected areas has been found to achieve from a substantial to a complete remission of dry skin, keratoses, warts and palmar and plantar hyperkeratosis. Used as a hair dressing, the compositions have been found to give the hair excellent grooming and luster.
Inventors
- 👤 Eugene J. Van Scott
- 👤 Ruey J. Yu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 21:04
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61K8/447; A61Q; A61Q19/00; A61Q19/007; A61K2800/00; A61K2800/20; A61K2800/28
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
100 words
A method for treating dry skin, actinic or non-actinic keratoses, warts, and palmar and plantar keratoses skin conditions, said method comprising topically applying to the involved skin a symptom alleviating and therapeutically effective amount of a medicinal composition containing from about 0.1 to 30% by weight of at least one compound selected from the group consisting of cysteic acid, cysteine sulfinic acid and homocysteic acid and chelates of said compound with at least one metallic compound selected from the group consisting of ferric chloride, copper sulfate, copper carbonate, zinc sulfate, zinc oxide, zinc chloride, aluminum chlorohydrate, and aluminum zinc sulfate.
Claim 2
Independent Claim
100 words
A method for treating dry skin, actinic or non-actinic keratoses, warts, and palmar and plantar keratoses skin conditions, said method comprising topically applying to the involved skin a symptom alleviating and therapeutically effective amount of a medicinal composition containing from about 0.1 to 30% by weight of at least one compound selected from the group consisting of cysteic acid, cysteine sulfinic acid and homocysteic acid and chelates of said compound with at least one metallic compound selected from the group consisting of ferric chloride, copper sulfate, copper carbonate, zinc sulfate, zinc oxide, zinc chloride, aluminum chlorohydrate, and aluminum zinc sulfate.
Claim 3
Dependent Claim
20 words
The method of claim 1 wherein said compound is present in an amount of from 0.2 to 20% by weight.
Claim 4
Dependent Claim
24 words
The method of claim 1 wherein a plurality of said compounds are present in a concentration of no more than about 20% by weight.
Claim 5
Dependent Claim
29 words
The method of claim 1 wherein said compound is present in a concentration of from 0.5 to 20% and said method comprises the treatment of actinic and non-actinic keratoses.
Claim 6
Dependent Claim
32 words
The method of claim 1 wherein said compound is present in a concentration of from 5 to 30% and said method comprises the method of treatment of warts, palmar, and plantar keratoses.
Claim 7
Dependent Claim
27 words
The method of claim 1 wherein said composition further comprises a liquid solution containing water present in from 40 to 90% by weight of the total composition.
Claim 8
Dependent Claim
13 words
The method of claim 1 wherein said medicinal composition is in powder form.
Claim 9
Dependent Claim
12 words
The method of claim 1 wherein said medicinal composition is a gel.
Claim 10
Dependent Claim
13 words
The method of claim 1 wherein said medicinal composition is a water-washable cream.
Claim 11
Independent Claim
117 words
A method for treating dry skin, actinic and non-actinic keratoses, warts, palmar and plantar keratoses, said method comprising topically applying to the involved skin a symptom alleviating and therapeutically effective amount of a medicinal composition containing from about 0.1 to about 30% by weight of at least one compound selected from the group consisting of a reaction product of cysteic acid, cysteine sulfinic acid and homocysteic acid with a base selected from the group consisting of an organic primary, secondary, or tertiary alkylamine, alkanolamine, diamine, dialkylamine, dialkanolamine, alkylalkanolamine, trialkylamine, trialkanolamine, dialkylalkanolamine, or alkydialkanolamine wherein the alkyl or alkanol substituent has from 1 to 10 carbon atoms, an organic quaternary ammonium hydroxide compound, sodium hydroxide, and potassium hydroxide.
Claim 12
Independent Claim
117 words
A method for treating dry skin, actinic and non-actinic keratoses, warts, palmar and plantar keratoses, said method comprising topically applying to the involved skin a symptom alleviating and therapeutically effective amount of a medicinal composition containing from about 0.1 to about 30% by weight of at least one compound selected from the group consisting of a reaction product of cysteic acid, cysteine sulfinic acid and homocysteic acid with a base selected from the group consisting of an organic primary, secondary, or tertiary alkylamine, alkanolamine, diamine, dialkylamine, dialkanolamine, alkylalkanolamine, trialkylamine, trialkanolamine, dialkylalkanolamine, or alkydialkanolamine wherein the alkyl or alkanol substituent has from 1 to 10 carbon atoms, an organic quaternary ammonium hydroxide compound, sodium hydroxide, and potassium hydroxide.
Claim 13
Dependent Claim
63 words
The method of claim 10 wherein the reaction product comprises a reaction product of a member selected from the group consisting of cysteic acid, cysteine sulfinic acid, homocysteic acid and a base selected from the group consisting of methylamine, ethylamine, ethanolamine, ethylenediamine, 1,2-diaminopropane, dimethylamine, diethylamine, diethanolamine, di-isopropanolamine, N-methylethanolamine, N-ethylethanolamine, trimethylamine, triethylamine, tripropylamine, N-ethyldicyclohexylamine, tri-isooctylamine, tri-isononylamine, tri-isodecylamine, triethanolamine, N-methyldiethanolamine, N-ethyldiethanolamine, N,N-dimethylethanolamine, N,N-diethylethanolamine and tri-isopropanolamine.
Claim 14
Dependent Claim
27 words
The method of claim 10 wherein said quaternary ammonium hydroxide compound comprises a member selected from the group consisting of tetramethylammonium hydroxide, tetrapropylammonium hydroxide, and basic choline.
References Cited (Backward Citations)
US4053630A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-23 | 1984-03-24 | 1984-09-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-23 | 1988-03-24 | 1988-09-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-23 | 1992-03-24 | 1992-09-23 | $7700.00 | Window Closed / Lapsed |