US4221793A
Expired / Lapsed
US
⏱️ 0.0 years remaining
N,N'-Disubstituted piperazine derivative
Assignee: Hoechst AG
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Filing: 1978-12-21
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Granted: 1980-09-09
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Expires: 1998-12-21
Abstract
Abstract A compound of the formula ##STR1## or its acid addition salt with a physiologically compatible acid, a process for its preparation by a reaction selected from the group consisting of (a) reacting N-benzyl-piperazine and 5-methoxycumarilic acid (a1) at an elevated temperature in the absence of a condensation agent, (a2) at a temperature of at least 15° C. in the presence of a condensation agent; (b) reacting N-benzyl-piperazine with an activated derivative of 5-methoxy-cumarilic acid; (c) N-(5-methoxycumaroyl)-piperazine with a benzyl compound selected from the group consisting of benzyl halide, benzylalkyl sulfonate and benzyl-aryl sulfonate and a pharmaceutical composition containing said compounds.
Inventors
- 👤 Rolf-Ortwin Weber
- 👤 Klaus Perrey
- 👤 Wolfrad von Rechenberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 11:14
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/82; C07D307/84; C07D307/85; A; A61; A61P; A61P25/00; A61P25/24; A61P25/26
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
16 words
A compound of the formula ##STR3## or its acid addition salt with a physiologically compatible acid.
Claim 2
Dependent Claim
16 words
A compound of the formula ##STR3## or its acid addition salt with a physiologically compatible acid.
Claim 3
Dependent Claim
48 words
A composition containing as an essential ingredient a therapeutically active amount of a compound as claimed in claim 1 wherein the therapeutically active amount of the compound as claimed in claim 1 is in the form of a dosage unit in an amount between 10 and 100 mg.
References Cited (Backward Citations)
US4115569A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-09 | 1984-03-10 | 1984-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-09 | 1988-03-10 | 1988-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-09 | 1992-03-10 | 1992-09-09 | $7700.00 | Window Closed / Lapsed |