US4221785A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti-inflammatory and anti-ulcer compounds and process
Assignee: JRJ SORENSON CORP
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Filing: 1978-05-30
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Granted: 1980-09-09
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Expires: 1998-05-30
Abstract
Abstract Disclosed herein are anti-inflammatory and anti-ulcer copper coordination compounds and a process for using them in the treatment of arthritis and gastrointestinal ulcers in animal bodies. The copper coordination compounds utilized are the reaction products of copper salts with: 1. aromatic carboxylic acids or their alkaline earth salts; 2. heterocyclic carboxylic acids or their alkaline earth salts; 3. amino acids or their alkaline earth salts; 4. amines; and 5. suitably substituted steroids. The process disclosed comprises administering to experimental animals, orally or parentrally (subcutaneously), in controlled dosages, the aforementioned copper coordination compounds for the treatment of inflammation (i.e., arthritis) and ulcers of the gastrointestinal tract.
Inventors
- 👤 John R. J. Sorenson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 21:45
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/60; C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/14; C07D231/28; C07D231/30; C07D231/32; C07D231/34
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
83 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with an aromatic carboxylic acid or alkaline earth salt thereof selected from the grou consisting of 3,5-diisopropylsalicylic acid, acetylsalicylic acid and salicylic acid and alkaline earth salts thereof, the amount of said copper coordination compound administered to said animal body being about 2.0 to 165 mg per kilogram of body weight.
Claim 2
Independent Claim
83 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with an aromatic carboxylic acid or alkaline earth salt thereof selected from the grou consisting of 3,5-diisopropylsalicylic acid, acetylsalicylic acid and salicylic acid and alkaline earth salts thereof, the amount of said copper coordination compound administered to said animal body being about 2.0 to 165 mg per kilogram of body weight.
Claim 3
Dependent Claim
21 words
The method of claim 1 wherein the copper salt is selected from the group consisting of cupric chloride and cupric acetate.
Claim 4
Independent Claim
69 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with 3,5-diisopropylsalicylic acid, acetylsalicylic acid or salicylic acid and the alkaline earth salts thereof, the amount of said copper coordination compound administered to said animal body being about 2.0 to 165 mg per kilogram of body weight.
Claim 5
Independent Claim
69 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with 3,5-diisopropylsalicylic acid, acetylsalicylic acid or salicylic acid and the alkaline earth salts thereof, the amount of said copper coordination compound administered to said animal body being about 2.0 to 165 mg per kilogram of body weight.
Claim 6
Dependent Claim
21 words
The method of claim 3 wherein the copper salt is selected from the group consisting of cupric chloride and cupric acetate.
Claim 7
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with 3,5-diisopropylsalicylic acid or its alkaline earth salts.
Claim 8
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with 3,5-diisopropylsalicylic acid or its alkaline earth salts.
Claim 9
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with acetylsalicylic acid or its alkaline earth salts.
Claim 10
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with acetylsalicylic acid or its alkaline earth salts.
Claim 11
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with salicylic acid or its alkaline earth salts.
Claim 12
Independent Claim
40 words
A method for treating gastrointestinal ulcers in an animal body comprising: administering to said animal body, orally or parenterally, a copper coordination compound having anti-ulcergenic properties produced by reacting a copper salt with salicylic acid or its alkaline earth salts.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-09 | 1984-03-10 | 1984-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-09 | 1988-03-10 | 1988-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-09 | 1992-03-10 | 1992-09-09 | $7700.00 | Window Closed / Lapsed |