US4214095A
Expired / Lapsed
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Chlorobenzyl phenoxy alkoxylates
Assignee: Siegfried AG
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Filing: 1979-01-25
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Granted: 1980-07-22
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Expires: 1999-01-25
Abstract
Abstract Novel compounds of the formula (1) <IMAGE> (1) wherein R1 and R2 are different lower alkyls and R3 is a lower alkyl or a methyl pyridine group, and the acid addition salts of formula (1) compounds when R3 is methyl pyridine. The novel compounds have an asymmetric C-atom and may be in the form of the D,L racemates or the D or L stereoisomers. These compounds are useful in the treatment of hypercholesterolemia and hyperlipidemia because of their high effectiveness in reducing the level of cholesterol and lipids in the blood combined with very low general toxicities and substantially reduced hepatomegalitic effects.
Inventors
- 👤 Kurt Thiele
- 👤 Quazi Ahmed
- 👤 Rudolf Adrian
- 👤 Ulrich Jahn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 06:38
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/28; C07D213/30; A; A61; A61P; A61P3/00; A61P3/06; C07C; C07C205/00; C07C205/27; C07C205/35; C07C205/36; C07C205/37; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07C59/68
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
65 words
A compound of the formula (1) ##STR16## wherein R 1 and R 2 are different alkyls of from 1 to 4 carbon atoms and R 3 is selected from the group consisting of alkyls having from 1 to 4 carbon atoms and methyl pyridine; and the acid addition salts of said formula (1) compound with a pharmaceutically acceptable acid when R 3 is methyl pyridine.
Claim 2
Dependent Claim
65 words
A compound of the formula (1) ##STR16## wherein R 1 and R 2 are different alkyls of from 1 to 4 carbon atoms and R 3 is selected from the group consisting of alkyls having from 1 to 4 carbon atoms and methyl pyridine; and the acid addition salts of said formula (1) compound with a pharmaceutically acceptable acid when R 3 is methyl pyridine.
Claim 3
Dependent Claim
20 words
The compound of claim 1 wherein R 3 is an alkyl selected from the group consisting of propyl and butyl.
Claim 4
Dependent Claim
18 words
The compound of claim 2 wherein R 2 is selected from the group consisting of ethyl and propyl.
Claim 5
Dependent Claim
10 words
The compound of claim 2 wherein R 3 is ethyl.
Claim 6
Dependent Claim
22 words
The compound of formula (2) ##STR17## in the form of the D,L-racemate and the D- and L-stereoisomers of the formula (2) compound.
Claim 7
Dependent Claim
22 words
The compound of formula (2) ##STR17## in the form of the D,L-racemate and the D- and L-stereoisomers of the formula (2) compound.
Claim 8
Dependent Claim
44 words
A compound of the formula ##STR18## wherein X is selected from the group consisting of alkyls having from 1 to 4 carbon atoms and methyl pyridine; and the acid addition salts of said compound with a pharmaceutically acceptable acid when X is methyl pyridine.
Claim 9
Dependent Claim
44 words
A compound of the formula ##STR18## wherein X is selected from the group consisting of alkyls having from 1 to 4 carbon atoms and methyl pyridine; and the acid addition salts of said compound with a pharmaceutically acceptable acid when X is methyl pyridine.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-07-22 | 1984-01-21 | 1984-07-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-07-22 | 1988-01-21 | 1988-07-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-07-22 | 1992-01-21 | 1992-07-22 | $7700.00 | Window Closed / Lapsed |