US4210644A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Male contraception
Assignee: Johns Hopkins University
•
Filing: 1978-02-23
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Granted: 1980-07-01
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Expires: 1998-02-23
Abstract
Abstract A method of affecting male contraception which comprises subdermally implanting in the male an effective amount of an androgen and an estrogen in one or more slow release capsules. The combination of androgen and estrogen may also be used to enhance libido in an aging male.
Inventors
- 👤 Larry L. Ewing
- 👤 Claude Desjardins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 00:17
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K31/00; A61K31/56; A61K31/565
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
94 words
A method of affecting male contraception which comprises subdermally implanting in the male a contraceptively effective amount of a synergistically active mixture of an androgen and an estrogen in one or more slow release capsules, the ratio of androgen to estrogen being in the range of 250 to 1 and 500 to 1, and permitting the androgen and estrogen to be continuously released at relatively constant rates for the desired length of time, said method being characterized by providing effective contraception without chronic elevation of the androgen and estrogen content in the peripheral blood.
Claim 2
Independent Claim
94 words
A method of affecting male contraception which comprises subdermally implanting in the male a contraceptively effective amount of a synergistically active mixture of an androgen and an estrogen in one or more slow release capsules, the ratio of androgen to estrogen being in the range of 250 to 1 and 500 to 1, and permitting the androgen and estrogen to be continuously released at relatively constant rates for the desired length of time, said method being characterized by providing effective contraception without chronic elevation of the androgen and estrogen content in the peripheral blood.
Claim 3
Dependent Claim
24 words
The method of claim 1 wherein the androgen is testosterone and the estrogen is estradiol and these are implanted in separate slow release capsules.
Claim 4
Dependent Claim
82 words
A contraceptive product comprising a synergistic combination of a contraceptively effective amount of testosterone and estradiol in the same or separate slow release capsules suitable for subdermal implantation such that the testosterone and estradiol are continuously released at relatively constant rates, the ratio of testosterone to estradiol being in the range of 250 to 1 and 500 to 1 and the product being further characterized by providing effective contraception without chronic elevation of the androgen and estrogen content in the peripheral blood.
Claim 5
Dependent Claim
82 words
A contraceptive product comprising a synergistic combination of a contraceptively effective amount of testosterone and estradiol in the same or separate slow release capsules suitable for subdermal implantation such that the testosterone and estradiol are continuously released at relatively constant rates, the ratio of testosterone to estradiol being in the range of 250 to 1 and 500 to 1 and the product being further characterized by providing effective contraception without chronic elevation of the androgen and estrogen content in the peripheral blood.
Claim 6
Independent Claim
76 words
A method of enhancing sexual libido in an aging male which comprises subdermally implanting in said male a libido-enhancing amount of a synergistically active mixture of an androgen and an estrogen in one or more slow release capsules, the ratio of androgen to estrogen being in the range of 250 to 1 and 500 to 1, and permitting the androgen and estrogen to be continuously released at relatively constant rates for the desired length of time.
Claim 7
Independent Claim
76 words
A method of enhancing sexual libido in an aging male which comprises subdermally implanting in said male a libido-enhancing amount of a synergistically active mixture of an androgen and an estrogen in one or more slow release capsules, the ratio of androgen to estrogen being in the range of 250 to 1 and 500 to 1, and permitting the androgen and estrogen to be continuously released at relatively constant rates for the desired length of time.
Claim 8
Dependent Claim
24 words
The method of claim 4 wherein the androgen is testosterone and the estrogen is estradiol and these are implanted in separate slow release capsules.
Claim 9
Dependent Claim
65 words
A product for enhancing sexual libido in the aging male comprising a synergistic combination of a libido-enhancing amount of testosterone and estradiol in the same or separate slow release capsules suitable for subdermal implantation, such that the testosterone and estradiol are continuously released at relatively constant rates, the ratio of testosterone to estradiol being in the range of 250 to 1 and 500 to 1.
Claim 10
Dependent Claim
65 words
A product for enhancing sexual libido in the aging male comprising a synergistic combination of a libido-enhancing amount of testosterone and estradiol in the same or separate slow release capsules suitable for subdermal implantation, such that the testosterone and estradiol are continuously released at relatively constant rates, the ratio of testosterone to estradiol being in the range of 250 to 1 and 500 to 1.
References Cited (Backward Citations)
US3279996A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-07-01 | 1983-12-31 | 1984-07-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-07-01 | 1987-12-31 | 1988-07-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-07-01 | 1991-12-31 | 1992-07-01 | $7700.00 | Window Closed / Lapsed |