US4208406A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition for the treatment and prevention of skin, eye and mucosal inflammation
Assignee: CEHOVIC GEORGES 7 RESIDENCE de la VALLEE 92120 PALAISEAU FRANCE
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Filing: 1977-07-14
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Granted: 1980-06-17
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Expires: 1997-07-14
Abstract
Abstract Composition for treatment or prevention of skin, eye or mucosal inflammation in human and animals, especially but not exclusively by external topical application comprising an effective amount of a cyclic nucleotide derivative having the following structural formula: ##STR1## wherein R 1 and R 2 , either are both a butyryl radical or one stands for a hydrogen atom and the other for a butyryl radical or both hydrogen atom; this compound may be used as such or in the form of any pharmaceutically acceptable salt of the same. The compounds of the general formula are 3', 5' adenosine monophosphate of cAMP derivatives.
Inventors
- 👤 Eugene Lapinet
- 👤 Georges Cehovic
- 👤 Theodore Posternak
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 15:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; C07H19/20
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
67 words
Composition for treatment of inflammation of skin, eye and mucosa in animals especially, but not exclusively, by external topical application comprising an effective amount of cyclic nucleotide having the following structural formula: ##STR8## wherein R 1 and R 2 , either are both a butyryl radical or one stands for a hydrogen atom and the other for a butyryl radical any pharmaceutically acceptable salt of the same.
Claim 2
Dependent Claim
67 words
Composition for treatment of inflammation of skin, eye and mucosa in animals especially, but not exclusively, by external topical application comprising an effective amount of cyclic nucleotide having the following structural formula: ##STR8## wherein R 1 and R 2 , either are both a butyryl radical or one stands for a hydrogen atom and the other for a butyryl radical any pharmaceutically acceptable salt of the same.
Claim 3
Independent Claim
64 words
The method of treating inflammation of skin, eye and mucosa in animals comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR9## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
Claim 4
Independent Claim
64 words
The method of treating inflammation of skin, eye and mucosa in animals comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR9## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
Claim 5
Independent Claim
61 words
The method of reducing the histamine level in animals comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR10## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
Claim 6
Independent Claim
61 words
The method of reducing the histamine level in animals comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR10## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
Claim 7
Independent Claim
65 words
The method of treatment to protect against inflammation of skin, eye and mucosa comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR11## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
Claim 8
Independent Claim
65 words
The method of treatment to protect against inflammation of skin, eye and mucosa comprising the administration in a pharmaceutically acceptable carrier of an effective amount of a composition having the following structural formula: ##STR11## wherein R 1 and R 2 are both butyryl radicals, or one is a hydrogen atom and the other is a butyryl radical or a pharmaceutically acceptable salt of the same.
References Cited (Backward Citations)
US3856776A
Cited
US3860706A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-06-17 | 1983-12-17 | 1984-06-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-06-17 | 1987-12-17 | 1988-06-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-06-17 | 1991-12-17 | 1992-06-17 | $7700.00 | Window Closed / Lapsed |