US4206205A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Monosaccharide and aglycone derivatives of C-076
Assignee: Merck and Co Inc
•
Filing: 1978-04-17
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Granted: 1980-06-03
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Expires: 1998-04-17
Abstract
Abstract Derivatives of C-076 are described in which the C-076 molecule, a series of macrolides in which one of the substituents is a 4-( alpha -L-oleandrosyl)- alpha -L-oleandrose has one or both of the carbohydrate moieties removed therefrom. The compounds thus produced have profound anthelmintic, insecticidal, ectoparasiticidal and acaracidal activity and compositions for such use are also disclosed.
Inventors
- 👤 Helmut H. Mrozik
- 👤 George Albers-Schonberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 15:06
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/22; A; A01; A01N; A01N43/00; A01N43/90; C07H; C07H17/00; C07H17/04; C07H17/08; C12; C12P; C12P17/00; C12P17/18; C12P17/181; C12P19/00; C12P19/44; C12P19/60; C12P19/62; C12P19/623
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
57 words
A compound having the formula: ##STR3## wherein R is hydrogen or α-L-oleandrosyl of the structure: ##STR4## and wherein the broken line indicates a single or a double bond; R 1 is hydroxy and is present only when said broken line indicates a single bond; R 2 is iso-propyl or sec-butyl; and R 3 is methoxy or hydroxy.
Claim 2
Dependent Claim
57 words
A compound having the formula: ##STR3## wherein R is hydrogen or α-L-oleandrosyl of the structure: ##STR4## and wherein the broken line indicates a single or a double bond; R 1 is hydroxy and is present only when said broken line indicates a single bond; R 2 is iso-propyl or sec-butyl; and R 3 is methoxy or hydroxy.
Claim 3
Dependent Claim
10 words
The compound of claim 1 wherein R 2 is iso-propyl.
Claim 4
Dependent Claim
10 words
The compound of claim 1 wherein R 2 is sec-butyl.
Claim 5
Dependent Claim
10 words
The compound of claim 3 which is C-076 Ala monosaccharide.
Claim 6
Dependent Claim
10 words
The compound of claim 3 which is C-076 Ala aglycone.
Claim 7
Dependent Claim
10 words
The compound of claim 3 which is C-076 A2a monosaccharide.
Claim 8
Dependent Claim
10 words
The compound of claim 3 which is C-076 A2a aglycone.
Claim 9
Dependent Claim
10 words
The compound of claim 3 which is C-076 B1a monosaccharide.
Claim 10
Dependent Claim
10 words
The compound of claim 3 which is C-076 B1a aglycone.
Claim 11
Dependent Claim
10 words
The compound of claim 3 which is C-076 B2a monosaccharide.
Claim 12
Dependent Claim
10 words
The compound of claim 3 which is C-076 B2a aglycone.
Claim 13
Dependent Claim
15 words
An anti-parasitic composition which comprises an inert carrier and the monosaccharide or aglycone of C-076.
Claim 14
Dependent Claim
15 words
An anti-parasitic composition which comprises an inert carrier and the monosaccharide or aglycone of C-076.
References Cited (Backward Citations)
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US3939144A
Cited
US3928387A
Cited
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Cited
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Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-06-03 | 1983-12-03 | 1984-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-06-03 | 1987-12-03 | 1988-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-06-03 | 1991-12-03 | 1992-06-03 | $7700.00 | Window Closed / Lapsed |