US4198515A
Expired / Lapsed
US
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Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids
Assignee: ER Squibb and Sons LLC
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Filing: 1978-12-08
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Granted: 1980-04-15
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Expires: 1998-12-08
Abstract
Abstract New mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids having the general formula ##STR1## are useful as hypotensive agents.
Inventors
- 👤 Miguel A. Ondetti
- 👤 Michael E. Condon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:26
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/18; C07D207/22; C07D207/24; A; A61; A61P; A61P9/00; A61P9/12; C07D211/00; C07D211/04; C07D211/68; C07D211/72; C07D211/78
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
43 words
A compound of the formula ##STR12## wherein R and R 2 each is hydrogen or lower alkyl; R 1 is hydrogen, hydroxy, halogen or lower alkoxy; R 3 is hydrogen m and n each is 0 or 1; and physiologically acceptable salts thereof.
Claim 2
Dependent Claim
43 words
A compound of the formula ##STR12## wherein R and R 2 each is hydrogen or lower alkyl; R 1 is hydrogen, hydroxy, halogen or lower alkoxy; R 3 is hydrogen m and n each is 0 or 1; and physiologically acceptable salts thereof.
Claim 3
Dependent Claim
10 words
A compound as in claim 1 wherein m is 0.
Claim 4
Dependent Claim
10 words
A compound as in claim 1 wherein m is 1.
Claim 5
Dependent Claim
16 words
A compound as in claim 1 wherein R, R 1 and R 3 each is hydrogen.
Claim 6
Dependent Claim
35 words
A compound as in claim 1 wherein R and R 2 each is hydrogen or lower alkyl; R 1 is hydrogen, hydroxy or halogen; R 3 is hydrogen; m is 0 and n is 1.
Claim 7
Dependent Claim
23 words
A compound as in claim 2 wherein R, R 1 , R 2 and R 3 each is hydrogen; and n is 1.
Claim 8
Dependent Claim
24 words
A compound as in claim 2 wherein R, R 1 and R 3 each is hydrogen; R 2 is methyl; and n is 1.
Claim 9
Dependent Claim
11 words
A compound as in claim 7 having the name S-4,5-dihydro-1-(3-mercapto-2-methyl-1-oxopropyl)-1H-pyrrole-2-carboxylic acid.
References Cited (Backward Citations)
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Cited
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US4113715A
Cited
US4129571A
Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-15 | 1983-10-15 | 1984-04-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-15 | 1987-10-15 | 1988-04-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-15 | 1991-10-15 | 1992-04-15 | $7700.00 | Window Closed / Lapsed |