US4198509A
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Mercaptoacylpiperazine carboxylic acid compounds
Assignee: ER Squibb and Sons LLC
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Filing: 1978-10-30
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Granted: 1980-04-15
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Expires: 1998-10-30
Abstract
Abstract The mercaptoacylpiperazine carboxylic acid compounds which have the formula ##STR1## wherein R, R 3 and R 4 each is hydrogen or lower alkyl; R 1 is lower alkyl; R 2 is hydrogen, lower alkanoyl, benzoyl or ##STR2## m is 0, 1 or 2; n is 1, 2 or 3, the sum of m+n being equal to 1, 2 or 3 and salts thereof, are useful as hypotensive agents.
Inventors
- 👤 Kathryn A. Losee
- 👤 Jack Bernstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 01:29
CPC Classifications
C; C07; C07D; C07D241/00; C07D241/02; C07D241/04; A; A61; A61P; A61P43/00; A61P9/00; A61P9/12
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
59 words
A compound of the formula ##STR11## wherein R, R 3 and R 4 each is hydrogen or lower alkyl; R 1 is lower alkyl; R 2 is hydrogen, lower alkanoyl, benzoyl or ##STR12## m is 0, 1 or 2; n is 1, 2 or 3, the sum of m+n being equal to 1, 2 or 3; and salts thereof.
Claim 2
Dependent Claim
59 words
A compound of the formula ##STR11## wherein R, R 3 and R 4 each is hydrogen or lower alkyl; R 1 is lower alkyl; R 2 is hydrogen, lower alkanoyl, benzoyl or ##STR12## m is 0, 1 or 2; n is 1, 2 or 3, the sum of m+n being equal to 1, 2 or 3; and salts thereof.
Claim 3
Dependent Claim
14 words
A compound as in claim 1 wherein R and R 2 each is hydrogen.
Claim 4
Dependent Claim
12 words
A compound as in claim 1 wherein R 2 is lower alkanoyl.
Claim 5
Dependent Claim
11 words
A compound as in claim 1 wherein R 1 is methyl.
Claim 6
Dependent Claim
42 words
A compound as in claim 1 wherein R and R 3 each is hydrogen; R 1 is lower alkyl; R 2 is hydrogen or lower alkanoyl; R 4 is hydrogen or lower alkyl; m is 0 or 1; and n is 1.
Claim 7
Dependent Claim
31 words
A compound as in claim 1 wherein R, R 3 and R 4 each is hydrogen; R 1 is methyl; R 2 is acetyl; and m and n each is 1.
Claim 8
Dependent Claim
30 words
A compound as in claim 1 wherein R, R 2 , R 3 and R 4 each is hydrogen; R 1 is methyl; and m and n each is 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-15 | 1983-10-15 | 1984-04-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-15 | 1987-10-15 | 1988-04-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-15 | 1991-10-15 | 1992-04-15 | $7700.00 | Window Closed / Lapsed |