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US4198401A Expired / Lapsed US ⏱️ 0.0 years remaining

Active plant extracts of hypoxidaceae and their use

Assignee: HOYER & Co KG GmbH
•
Filing: 1979-03-01
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Granted: 1980-04-15
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Expires: 1999-03-01
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Abstract

Abstract Plant material derived from the family Hypoxidaceae is heated at a temperature of at least 60 DEG C. for a sufficient period to ensure enzyme destruction and is then extracted at a temperature of 0 DEG -30 DEG C. with aqueous alcohol containing 30-75 volume percent ethanol for about 1 to 15 days to obtain a pharmaceutically active material.

Inventors

  • 👤 Karl H. Pegel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 04:00
CPC Classifications
A; A61; A61K; A61K36/00; A61K36/18; A61K36/185; A61K36/81; A61K36/88; A61K36/896

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 82 words
A process of combatting a human illness selected from the group consisting of inflammatory illness, gout and benign hypertrophy comprising administering to a patient suffering therefrom an effective amount of an extract of plant material of the family Hypoxidaceae prepared by a process comprising the steps of heating the plant material to at least 60° C. to deactivate the steroline specific degrative enzymes and thereafter extracting at 0° to 30° C. with aqueous alcohol containing 30-75 volume percent ethanol for 1-15 days.
Claim 2
Dependent Claim 82 words
A process of combatting a human illness selected from the group consisting of inflammatory illness, gout and benign hypertrophy comprising administering to a patient suffering therefrom an effective amount of an extract of plant material of the family Hypoxidaceae prepared by a process comprising the steps of heating the plant material to at least 60° C. to deactivate the steroline specific degrative enzymes and thereafter extracting at 0° to 30° C. with aqueous alcohol containing 30-75 volume percent ethanol for 1-15 days.
Claim 3
Dependent Claim 18 words
A process according to claim 1 wherein the effective amount is between 50 and 1000 mg a day.
Claim 4
Dependent Claim 14 words
A process according to claim 2 wherein the dosage is 300 mg a day.
Claim 5
Dependent Claim 12 words
A process according to claim 1 wherein the plant is Hypoxis rooperi.
Claim 6
Dependent Claim 13 words
A process according to claim 1 wherein the illness is an inflammatory illness.
Claim 7
Dependent Claim 11 words
A process according to claim 5 wherein the illness is arthritis.
Claim 8
Dependent Claim 13 words
A process according to claim 5 wherein the illness is a rheumatic illness.
Claim 9
Dependent Claim 11 words
A process according to claim 5 wherein the illness includes edema.
Claim 10
Dependent Claim 12 words
A process according to claim 5 wherein the plant is Hypoxis rooperi.
Claim 11
Dependent Claim 13 words
A process according to claim 1 wherein the illness is benigh prostate hypertrophy.
Claim 12
Dependent Claim 12 words
A process according to claim 10 wherein the plant is Hypoxis rooperi.
Claim 13
Dependent Claim 62 words
A pharmaceutical product comprising an extract of plant material of the family Hypoxidaceae prepared by a process comprising the steps of heating the plant material to at least 60° C. to deactivate the steroline specific degrative enzymes and thereafter extracting at 0° to 30° C. with aqueous alcohol containing 30-75 volume percent ethanol for 1-15 days together with a pharmaceutically acceptable carrier.
Claim 14
Dependent Claim 62 words
A pharmaceutical product comprising an extract of plant material of the family Hypoxidaceae prepared by a process comprising the steps of heating the plant material to at least 60° C. to deactivate the steroline specific degrative enzymes and thereafter extracting at 0° to 30° C. with aqueous alcohol containing 30-75 volume percent ethanol for 1-15 days together with a pharmaceutically acceptable carrier.
Claim 15
Dependent Claim 14 words
A pharmaceutical product according to claim 12 wherein the plant material is Hypoxis rooperi.

References Cited (Backward Citations)

GB1259503A Cited
DE2015877C3 Cited
DE2312285A1 Cited
GB1417272A Cited
US3933789A Cited
DE2251695A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-04-15 1983-10-15 1984-04-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-04-15 1987-10-15 1988-04-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-04-15 1991-10-15 1992-04-15 $7700.00 Window Closed / Lapsed

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