US4198206A
Expired / Lapsed
US
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Method for preparing a platelet reference control
Assignee: Individual
•
Filing: 1978-08-30
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Granted: 1980-04-15
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Expires: 1998-08-30
Abstract
Abstract A platelet reference control method of preparation wherein aldehyde-reacted platelets are suspended in a phosphate buffer fortified with glycine and ethylene glycol.
Inventors
- 👤 Wayne L. Ryan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:38
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N2496/00; G01N2496/05; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/101666; Y10T436/107497; Y10T436/108331
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
130 words
A method for preparing a platelet reference control comprising: reacting platelets with an aldehyde and removing the aldehyde by centrifugation suspending the aldehyde-reacted platelets that have been washed in an amino acid solution in a solution of: (a) a first member selected from the class consisting of glycine and alanine having a molarity in the range of about 0.10 to about 0.30, (b) a second member selected from the class consisting of ethylene glycol, glycerine and methanol having a molarity in the range of about 0.5 to about 1.5, (c) a third member selected from the class of sodium chloride and sodium phosphate having a molarity of from about 0.1 to about 1.0 and a pH in the range of at least about 6.5-7.4, and (d) a solid polyethylene glycol.
Claim 2
Independent Claim
130 words
A method for preparing a platelet reference control comprising: reacting platelets with an aldehyde and removing the aldehyde by centrifugation suspending the aldehyde-reacted platelets that have been washed in an amino acid solution in a solution of: (a) a first member selected from the class consisting of glycine and alanine having a molarity in the range of about 0.10 to about 0.30, (b) a second member selected from the class consisting of ethylene glycol, glycerine and methanol having a molarity in the range of about 0.5 to about 1.5, (c) a third member selected from the class of sodium chloride and sodium phosphate having a molarity of from about 0.1 to about 1.0 and a pH in the range of at least about 6.5-7.4, and (d) a solid polyethylene glycol.
Claim 3
Dependent Claim
25 words
The method of claim 1 in which said first member is glycine, said second member is ethylene glycol and said third member is sodium phosphate.
Claim 4
Dependent Claim
17 words
The method of claim 1 in which said platelets are suspended before contact with said polyethylene glycol.
Claim 5
Dependent Claim
31 words
The method of claim 3 in which said platelet suspension step prior to contact with polyethylene glycol is performed in a period of the order of at least about one hour.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-15 | 1983-10-15 | 1984-04-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-15 | 1987-10-15 | 1988-04-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-15 | 1991-10-15 | 1992-04-15 | $7700.00 | Window Closed / Lapsed |