US4197290A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Vaccine
Assignee: Individual
•
Filing: 1978-09-29
•
Granted: 1980-04-08
•
Expires: 1998-09-29
Abstract
Abstract A vaccine effective against challenge infections, such as bovine mastitis is prepared from Staphyloccus aureus or Staphylococcus epidermidis strain.
Inventors
- 👤 Kosaku Yoshida
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 16:07
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/085; Y; Y10; Y10S; Y10S424/00; Y10S424/823
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
50 words
A method of producing a heat-killed vaccine from a strain of S. epidermidis ATCC 31432 which comprises: a. culturing said S. epidermidis strain in a culture broth; b. isolating polysaccharide encapsulated S. epidermidis from said broth; and c. heat inactivating said polysaccharide encapsulated S. epidermidis and recovering said heat-killed vaccine.
Claim 2
Independent Claim
50 words
A method of producing a heat-killed vaccine from a strain of S. epidermidis ATCC 31432 which comprises: a. culturing said S. epidermidis strain in a culture broth; b. isolating polysaccharide encapsulated S. epidermidis from said broth; and c. heat inactivating said polysaccharide encapsulated S. epidermidis and recovering said heat-killed vaccine.
Claim 3
Dependent Claim
31 words
The method of claim 1, wherein said heat inactivated strain is injected into a host animal to induce an antibody response and the antibody containing serum from said host is recovered.
Claim 4
Independent Claim
52 words
A method of producing a polysaccharide vaccine characterized by active immunization activity to challenge infection, which comprises: a. culturing an S. epidermidis strain ATCC 31432 in a culture broth; b. isolating polysaccharide encapsulated epidermidis from said broth; and c. subjecting said cells to sonic oscillation and deproteonization and recovery of said polysaccharide.
Claim 5
Independent Claim
52 words
A method of producing a polysaccharide vaccine characterized by active immunization activity to challenge infection, which comprises: a. culturing an S. epidermidis strain ATCC 31432 in a culture broth; b. isolating polysaccharide encapsulated epidermidis from said broth; and c. subjecting said cells to sonic oscillation and deproteonization and recovery of said polysaccharide.
Claim 6
Dependent Claim
9 words
The vaccine produced by the method of claim 1.
Claim 7
Dependent Claim
9 words
The vaccine produced by the method of claim 2.
Claim 8
Dependent Claim
9 words
The vaccine produced by the method of claim 3.
Claim 9
Independent Claim
32 words
A method for immunizing bovines against challenge infection which comprises administering to said animal an amount of capsular polysaccharide derived from S. epidermidis ATCC 31432 sufficient to elicit an immunizing antibody response.
Claim 10
Independent Claim
32 words
A method for immunizing bovines against challenge infection which comprises administering to said animal an amount of capsular polysaccharide derived from S. epidermidis ATCC 31432 sufficient to elicit an immunizing antibody response.
Claim 11
Independent Claim
32 words
A method for immunizing bovines against challenge infection which comprises administering to said animal an amount of a heat inactivated encapsulated S. epidermidis ATCC 31432 sufficient to elicit an immunizing antibody response.
Claim 12
Independent Claim
32 words
A method for immunizing bovines against challenge infection which comprises administering to said animal an amount of a heat inactivated encapsulated S. epidermidis ATCC 31432 sufficient to elicit an immunizing antibody response.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-08 | 1983-10-08 | 1984-04-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-08 | 1987-10-08 | 1988-04-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-08 | 1991-10-08 | 1992-04-08 | $7700.00 | Window Closed / Lapsed |