US4196208A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Certain pyridyl esters of 4-(monoalkylamino) benzoic hydroxyalkanoic acids
Assignee: Wyeth Holdings LLC
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Filing: 1977-12-19
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Granted: 1980-04-01
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Expires: 1997-12-19
Abstract
Abstract This disclosure describes esters of 4-(monoalkylamino)benzoic acids with hydroxyalkanoic acids and derivatives, phenols, or 3-pyridinols useful as hypolipidemic agents.
Inventors
- 👤 Robert G. Shepherd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 18:07
CPC Classifications
C; C07; C07D; C07D257/00; C07D257/02; C07D257/04; C07C; C07C275/00; C07C275/46; C07C275/48; C07C275/54; C07C45/00; C07C45/45; C07D295/00; C07D295/16; C07D295/18; C07D295/182; C07D295/192
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
56 words
A compound of the formula: ##STR4## wherein R 1 is an unbranched or branched alkyl group of the formula C n H 2n+1 wherein n is an integer from 8 to 19, inclusive, and R 3 is 3-pyridyl, 5-methyl-3-pyridyl, 2,6-dimethyl-3-pyridyl, 6-methoxy-3-pyridyl, 2-hydroxy-3-pyridyl, 6-chloro-3-pyridyl, 4-carboxy-3-pyridyl, 5-carboxy-3-pyridyl or 4-cyano-3-pyridyl; and the pharmaceutically acceptable acid-addition and cationic salts thereof.
Claim 2
Dependent Claim
56 words
A compound of the formula: ##STR4## wherein R 1 is an unbranched or branched alkyl group of the formula C n H 2n+1 wherein n is an integer from 8 to 19, inclusive, and R 3 is 3-pyridyl, 5-methyl-3-pyridyl, 2,6-dimethyl-3-pyridyl, 6-methoxy-3-pyridyl, 2-hydroxy-3-pyridyl, 6-chloro-3-pyridyl, 4-carboxy-3-pyridyl, 5-carboxy-3-pyridyl or 4-cyano-3-pyridyl; and the pharmaceutically acceptable acid-addition and cationic salts thereof.
Claim 3
Dependent Claim
8 words
The compound according to claim 1; 3-pyridyl 4-(hexadecylamino)benzoate.
Claim 4
Dependent Claim
8 words
The compound according to claim 1; 6-chloro-3-pyridyl 4-(hexadecylamino)benzoate.
Claim 5
Dependent Claim
8 words
The compound according to claim 1; 2,6-dimethyl-3-pyridyl 4-(hexadecylamino)benzoate.
Claim 6
Dependent Claim
8 words
The compound according to claim 1; 5-carboxy-3-pyridyl 4-(hexadecylamino)benzoate.
Claim 7
Dependent Claim
8 words
The compound according to claim 1; 2-hydroxy-3-pyridyl 4-(hexadecylamino)benzoate.
Claim 8
Dependent Claim
32 words
The compound of treating hyperlipidemia and hyperlipoproteinemia and/or altering the lipoprotein pattern in a mammal comprising administering to said mammal an effective lipid-altering amount of a compound in accordance with claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-01 | 1983-10-01 | 1984-04-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-01 | 1987-10-01 | 1988-04-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-01 | 1991-10-01 | 1992-04-01 | $7700.00 | Window Closed / Lapsed |