US4196133A
Expired / Lapsed
US
⏱️ 0.0 years remaining
24,24-Difluoro-25-hydroxycholecalciferol
Assignee: Wisconsin Alumni Research Foundation
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Filing: 1979-03-05
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Granted: 1980-04-01
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Expires: 1999-03-05
Abstract
Abstract The invention provides a new derivative of vitamin D3, 24,24-difluoro-25-hydroxycholecalciferol. The compound is characterized by vitamin D-like activity in its ability to increase intestinal calcium transport, increase serum calcium and inorganic phosphorous concentration and to prevent the development of rickets. It would find ready application as a substitute for vitamin D3 and in the treatment of disease states evincing calcium-phosphorous imbalance and which are non-responsive to vitamin D3 therapy.
Inventors
- 👤 Hector F. DeLuca
- 👤 Nobuo Ikekawa
- 👤 Yoko Tanaka
- 👤 Yoshiro Kobayashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 18:42
CPC Classifications
C; C07; C07J; C07J9/00; A; A61; A61P; A61P3/00; A61P3/02; A61P3/12; A61P3/14
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
5 words
24,24-difluoro-25-hydroxy vitamin D 3 .
Claim 2
Dependent Claim
5 words
24,24-difluoro-25-hydroxy vitamin D 3 .
Claim 3
Dependent Claim
5 words
24,24-difluoro-25-hydroxy previtamin D 3 .
Claim 4
Dependent Claim
5 words
24,24-difluoro-25-hydroxy previtamin D 3 .
Claim 5
Dependent Claim
11 words
Compounds having the formula ##STR2## where R is hydrogen or acetyl.
Claim 6
Dependent Claim
11 words
Compounds having the formula ##STR2## where R is hydrogen or acetyl.
References Cited (Backward Citations)
US3993675A
Cited
US4069321A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-01 | 1983-10-01 | 1984-04-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-01 | 1987-10-01 | 1988-04-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-01 | 1991-10-01 | 1992-04-01 | $7700.00 | Window Closed / Lapsed |